Is their a slow release form of [ UK ] of Pramipexole ?

[bambisoloved]

I take 6 tablets [ 0.088mg ] at night but was wondering if this is available

Bambisoloved

[Tpebop]

Hi Bambisoloved! I too am using Pramipexole. For ages I've been on x4 0.088mg but now am having to take a fifth every now and then. According to the Site Elders (respect due dudes and dudesses!) FIVE tabs is the MAXIMUM RLS sufferers should take (it's a Parkinson's Disease drug) so be careful. Like you I'm wondering what happens next.

There IS a slow release pramipexole available in the UK (it's commonly used in the 'States) and at least one site user uses it. However it looks as if it is very expensive in comparison to the tablets, so GPs may be reluctant to prescribe it. Visit your GP and ask them about it and let us know how you got on.

All the best, Tpebop, Kent, Britain.

[Hidden in reply to Tpebop]

I split my doses at times. I don't have a choice if I know that I

have to be still during a presentation or a theater event. It

works for me....But....I never did get the "go ahead" from

my doctor to do so. Also, I find that by 2am my legs start in..

if I do that.

I'm starting to really think that this is a disability that requires us

to sleep when our bodies decide it's time.. I am so accident prone

and have experienced a couple events that makes me wonder

if I am going to be able to keep at my job as much as I am.

I fell asleep while reading to some of my developmentally

disabled adult clients.. They woke me up laughing that I let

out a snore. Wow, I didn't think that I ever snored.

I knew that this event was on the schedule so I took a .0125

of Pramipexole an hour before my reading marathon started.

[Pete-1]

Yes, its known as Mirapxin or Pramipexole prolonged-release. I've been taking it for a few months now - no problems.

These tablets are meant to last 24 hours and so only 1 tablet per day is required.

[Pete-1 in reply to Pete-1]

Forgot to mention that I take Pramipexole primarily for Parkinson's Disease rather than RLS, although if I don't take Pramipexole I get RLS as one of the PD symptoms. So I will have been given a higher dose. I don't know if there is a low enough extended-release version Pramipexole suitable of RLS.

[nightdancer in reply to Pete-1]

yes, there is a lower dose for RLS only.

[madfol]

Hi, Yes, I also have been on 5 of Prami. for about 3 years., However for the past 2 years I suffer severe augmentation in the daytime.I can tolerate this though as I would prefer to be able to sleep at night,and in the daytime one can always walk around. That is, unless one is stuck in a traffic jam on M25 - horrendous, there is nowhere to go and you can't get even get out of the car!!! A living nightmare!!!

A while ago I was offered a patch, I think it was called 'Transdermal', but I didn't take it as the side effects of Prami. are hard enought to cope with and I went with the premise of 'Better off with the Devil you know, then the Devil you don't!'

In September I was prescribed Gabapentin capsules, but at the same time I began to suffer from an incredibly painful trapped Sciatic Nerve, and was eventually prescribed Oramorph, and underwent an Epidural Steroid Injection. Unfortunately this didn't immediately improve the pain, but 5 months down the line I feel the trapped nerve is starting to right itself. What was truly awful was when my RLS kicked in and joined the nerve pain - it really was excruciating!

Never mind, as I always try to remember and tell myself - stop moaning, at least I have 2 legs, and certainly there are many others worse off than me!

To get back to the point - I was too nervous to try the Gabapentin, alongside Oramorph and numerous Paracetamol, which I knew were safe,but If my trapped nerve continues to improve I do plan to start on the Gabpentin, and have already asked, and had lots of info. about it from this site.

In my experience however, the plain fact is that whatever medication we take for RLS, it seems that anything will lose it's effectiveness after a while, and we will either have to change or up dosage!

I'm afraid we're all in a 'No Win' situation until more research is done to find a cause and ultimately a cure!

By the way - a bit late, but Happy New Year to everoine!

[Hidden in reply to madfol]

Gabpentin caused me numbness in my leg, foot...

I gained weight, fast on that.

I was tired, numb and had a bad attitude while taking that.

My doctor pulled me off it. I lost the weight, it wasn't easy.

I still have some numbness in my foot.

Usually that's not the common side effect but I was the lucky one. haha.

I didn't realize how tired that made me until I quit with it.

I understand that Gabpentin is used very successfully for Shingles

over here in the USA. My daughter in law is using it for that currently.

She has no side effects other than being very tired.

[Hidden]

Hi all, I live in The Netherlands and use those tablets Pramipexole that last for 24 hours and I can tell you: for me it's heaven, I can sleep again!! I wish you the same.

[popank in reply to Hidden]

Apologies if I have mentioned this before, I have now been on Pramipexole for 3 months (lowest dosage) and getting generally a good nights sleep has been marvellous apart from the couple of trips to the loo, but I go straight back to sleep.

[madfol in reply to popank]

In reply to Popbank - Yes, I also started on 1 per day, but gradually needed more, by the time I get to 3 I was starting to half them , but eventually I had to take the max of 5.

If I can offer advice it would be that if you find your dose is not adequate, be very wary of increasing and increase as slowly as you can!

Good luck though, it is a good medication, and I too was over the moon when I first took it, after 21 yrs of not sleeping!

[patchworker]

I've been on pramipexole 0.52mg prolonged release tablets for two years now. I take two a day, one in the morning, one at night. They work wonderfully for me

They work better and for longer than anything else I've tried. Most things work for just a few months for me.

[Hidden in reply to patchworker]

=) that's such good news to hear! =)))

[ellie1]

ive been on praipexole for about 5 or 6 years and i called it the miracle drug best sleep i had in years but i become a terrible compulive gambler and i think everyone should be very aware of this medication now am in a worst situation with really bad restless legs and now in the arms

[Hidden]

Ellie...that's not good. I was warned about that.. and I could become

a sex maniac as well...

Thanks for sharing your story...

I laughed when the doctor told me that but I will take that seriously now.

I feel like crap too with my legs and more recently my shoulders, arms starting

in. My neck hurts a lot today because I wrestled around with that going on all

night. I was so upset all night about my body.

[nightdancer in reply to Hidden]

The compulsive side effects are VERY serious and must be taken SERIOUSLY. I know a woman who lost her house, etc and many more stories like that. be careful of that gambling!!!! and compulsive shopping and eating can happen, too.

[Hidden]

That's really upsetting to me Nightdancer. I didn't mean to mock anyone.

I did think that my doctor was joking me. =)

[Hidden in reply to Hidden]

My doctor too laughed when she was telling me side affects . It's serious for some people , but normally if your affected by a side affect like that , the doctor woud get you off them . I took seritine or something like that for depression and one side affect was sex but I went off it totally so I would think it funny if I get this new drug and it turns me the other way , I'm sure my partner would be happy , not all side affects are bad news , some are indeed very funny . I'm sure you wasn't mocking anyone . I have learnt very quickly on this site to take a lot of what one or two people say with a pinch of salt . There's always a bad egg in the box . Or someone that wants to upset the norm , or throw a negative On to a positive. Stay positive if it's funny laugh at it . I laugh all the time , I have too other wise it all gets too serious and that's when you get really down and I do anyway struggle to see past my restess legs . But each our own hay .

[peterk]

There is a slow release tablet of pramipexole and it is called Mirapexin. Hope this helps.

[Hidden]

they are the same med, just different brand names !

[bambisoloved]

Hello

Yes your right, ones a tablet and the other a slow release patch

I think people get confused between the brand name and the generic name

bambisoloved

[Hidden]

the 24 hour patch is the Neupro patch, ive used it before