Need some advice.....

[SurvivorD]

It has been four weeks that I have been weaning myself off the Pexola 1mg. I was on .50mg . Doctor has prescribed 50mg Pregabalin (Lyrica) which I have been taking for four nights with the Pexola and never had RL for two nights which was a blessing. Last night I decided to go cold turkey and get done with the Pexola. I am sure as many will testify, was a night of absolute hell! Rubbed cannabis oil on my legs, raised my legs and eventually took half a sleeping tablet (Inveral) which wasn't the best decision. I was now drowsy and not able to sleep so had a two fold problem.

Can anyone give me advise :

a) Should I carry on weaning myself off the Pexola for a longer period? I have been on this medication for over 20years and was definitely experiencing Augmentation.

b) Increase the pregabalin?

c) Carry on taking the Pexola with the Pregabalin for another two weeks.

I am going to The Kruger National Park for eight days and we will be in the car sight seeing most of the day........which isn't always a pleasant experience with RLS but so enjoy being there!! I don't want to be left in the camp while my family are out experiencing the Park. Could you please give me your personal and professional advise to help me enjoy my holiday and to get through the weaning off of the Pexola?

I am currently also taking Ferrous bisglycinate 24mg which includes Folic Acid 336 Vit B12 15 with Vit C 500mg daily.

Thank you kindly

[SueJohnson]

If you want to enjoy your vacation go back up to the amount you were last taking. After your vacation wean yourself slowly off it. 50 mg is below the starting dose of 75 mg so yes increase it to 75 mg. After you have been on it the 3 weeks you can increase it by 25 mg every two days up to 150 mg but I wouldn't increase it any more until you are off Pexola for several weeks and your symptoms have settled. That is good news that it is helping.

[SurvivorD in reply to SueJohnson]

Thank you for your wisdom and support 🙏 🙏

[Joolsg]

I agree with Sue. Go back to 0.5mg Pramipexole. Withdrawal after the last dose of Pramipexole is severe and lasts around a month with little to no sleep. Go on your holiday and time the withdrawal for when you aren't working or have no commitments.

[SurvivorD in reply to Joolsg]

Thank you for your wisdom and support 🙏 🙏