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Restless Legs Syndrome

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omeprazole

Pippins2 profile image
22 Replies

HI does Omeprazole trigger RLS ? Taken one tonight and legs going nuts ? Thankyou

Pipps

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22 Replies
Mopsy1950 profile image
Mopsy1950

Hi pippins 2 have been on omeprazole for many years hiatus hernia now take morning and night it has never affected my legs but we are all different

Marlayna profile image
Marlayna

yes! I had to stop it immediately.

Madlegs1 profile image
Madlegs1

Most of those PPIs set off RLS.

SueJohnson profile image
SueJohnson

It interferes with the absorption of iron but shouldn't cause your RLS to get worse, however everybody is different and it obviously is makin yours worse.

Joolsg profile image
Joolsg

Hi Pipps, the US foundation mentions that most PPI gastric meds trigger RLS. It seems to be the case for you.

martino profile image
martino

I take omeprazole without a detrimental RLS result. But mentioning that I should add that I take Nortriptylene without adversely affecting my legs. We are all different!

Whippetmama profile image
Whippetmama

i'm another that can't take it. I learned that the hard way.

Jumpey profile image
Jumpey

In theory it shouldn't. It doesn't for me. It does interfer with iron absorption. But listen to your body.It may not suit you.Try an H2

blocker like Cimitedine. Good luck.

SueJohnson profile image
SueJohnson in reply toJumpey

Cimetidine also inhibits the absorption of iron.

Jumpey profile image
Jumpey in reply toSueJohnson

It does but isn't as strong as the PPI s in terms of blocking acid so some absorption should be possible.

Mum007 profile image
Mum007

it does for me after a few days. I take esomeprazole and it appears ok but I also take iron (not at the same time) although I don’t take the ppi for longer than 2 weeks at a time. All the other ppi’s send my legs nuts. We are all different

Eryl profile image
Eryl

One of the side effect of Omeprazole is inflammation and as I believe that one of the main causes of RLS is systemic inflammation I wouldn't be at all surprised if your RLS got worse on omeprazole. You could eliminate your need for Omeprazole and eliminate your RLS by changing your diet and eliminating processed foods like bread and other wheat based products, refined sugars and starches and cutting down the use of refined seed oils.

charlie1234567890 profile image
charlie1234567890 in reply toEryl

I'm pretty sure omeprazole is an anti-inflammatory as are all ppi's. They use them for poison ivy outbreaks now.

Lola43 profile image
Lola43

Hi Pippins,

I took lanzoprazole last night (which is another PPI) and my legs and arms went absolutely crazy. Didn’t get any sleep at all. Think I’d rather have the gastritis!

I’m never taking it ever again. I’m also going to avoid food tonight .

So your not alone in your RLS going off the scale with a PPI .

Let’s hope for a better night tonight!

Lola xx

in reply toLola43

Hi Lola, you might want to try taking zinc carnosine for heartburn and Gastritis. Nothing short of a miracle for Gastritis. It’s by prescription in Japan. I take it the second I feel a tiny bit of heartburn. PPIs didn’t make my RLS worse as I recall, but it did give me pretty bad, all day, migraines. Took a while for me to make the connection.

Reflux is tough to control because in most cases it’s caused by a hiatal hernia which means that sphincter muscle which closes off the stomach and stops the acid from backing up into the esophagus isn’t working right. The stomach is literally bulging into the esophagus. So yes, good idea not to eat at night. For several weeks now I’ve been using a sleep wedge and love it. Also, sleeping on your left side should help greatly with reflux.

Never take any zinc product (not even cold-eez) on an empty stomach. It will give you mild nausea until you eat something. Also if you take more than 30 mg of zinc a day you should supplement with one or two milligrams of copper. They balance each other out. Zinc is considered a calming mineral while copper is more excitatory. We need both and want them in balance to feel great.

Lola43 profile image
Lola43 in reply to

thanks for this 😊. I’m going to order some zinc and copper! Lola x

in reply toLola43

Zinc is great by itself but I believe for Gastritis zinc carnosine is best. It should also be a bioavailable form of copper. Let me find a link for the zinc carnosine. Sadly it is my most expensive supplement.

Here is a link for it. With the 15% off code and free shipping for orders over $20 it is the cheapest I could find on the internet for the US: pureformulas.com/natures-li...

Lola43 profile image
Lola43 in reply to

thank you so much! Hopefully they will ship to UK - I will have a look . 😊

Lola x

HipHop1972 profile image
HipHop1972

Hi Pippins2. I was interested to read that you thought Omeprazole triggered your RLS, as I take 20mg of Omeprazole every morning for Reflux and my GP, although it’s very hard to see the same one twice, didn’t mention a possible link as a RLS trigger but it affects you and several others who have replied to you also noted a link.

Maybe I’ll stop taking it and see what happens, well Reflux will return yes, but can monitor RLS. Thank You Pippins2 for asking the question

SueJohnson profile image
SueJohnson

Gaviscon is a safe antacid.

BeachGolfer profile image
BeachGolfer

After taking Omeprazole I spent an entire night walking up and down the stairs, taking baths and walking from room to room. Never again!

Pippins2 profile image
Pippins2

Thankyou everyone for your replies I am no longer taking it x

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