Percocet during Pramipexole Withdrawal

[kturenne]

On Percocet 10mg at night to deal with augmentation from Pramipexole while waiting to get in to see a neurologist. What dose seems to work for people? Does it make you tired if you take it during the day? I’m experiencing Withdrawal during day now too.

[Joolsg]

Tough question.Everyone seems to have different experiences with withdrawal from dopamine agonists. But the majority will experience 24/7 withdrawal for around 2 weeks. So daytime withdrawal symptoms are common. If unbearable, you may need to take percocet in the daytime.

What dose of Pramipexole are you at now and are you reducing slowly by half a 0.088 pill every 2 weeks?

I used 50mg tramadol for 4 weeks when I reached the last dose of Ropinirole. I took 50mg every 4 hours and cannabis cigarettes.

Percocet ( oxycodone) can also help withdrawals but it might be better to start taking the drug that will replace Pramipexole. Will your doctors be prescibing Oxycodone or gabapentin/pregabalin?

Many people find that starting pregabalin or gabapentin 4 weeks before they drop the last dose of Pramipexole helps withdrawal.

[kturenne in reply to Joolsg]

I was taking 1mg. My Family Dr weaned me off Pramipexole over a 3 week span and was going to put me on Ropinerole. After reading about Augmentation and dealing w worsening symptoms I told her I wasn’t going to go back on any Dopamine drugs. I was on Pramipexole for 10 years. I read about opioid treatment so I started the Percocet on my own to help w withdrawal. I had some left over from a previous surgery. She referred me to a neurologist because she was unable to recommend any other options and didn’t feel comfortable prescribing anything else. I can’t get into a neurologist until end of October.

[Joolsg in reply to kturenne]

So you came off 1mg of Pramipexole in 3 weeks? That's scary. Most experts recommend taking a minimum of 6 months for someone on such a high dose. That's like going cold turkey and no wonder you have daytime withdrawals.

Have you had full panel fasting bloods? Raising serum ferritin above 100, preferably 200 helps the majority of RLS patients and is the first step recommended by the Mayo algorithm before meds. Iron infusions raise levels faster than oral supplements.

If raising ferritin doesn't help meds can be prescribed.

Pregabalin is now first line Treatment according to the Mayo guidelines so can you direct your family doctor to the guidelines and ask for Pregabalin?

You start taking 25mg at night and increase by 25mg every 2 or 3 days up to 150mg . It takes 3 weeks to be fully effective so hold off increasing above 150mg until you see if it helps.

In the meantime, medical cannabis and red vein borneo kratom can help severe withdrawal symptoms.

[kturenne]

No, my gp won’t rx or do anything else at this point- said go to neurologist. Can u get iron at pharmacy w/o a rx? Also, does anyone on this forum have recommendations of neurologists in NY who are well versed in RLS augmentation?

[SueJohnson]

David J. Dickoff

[phone]

Yonkers

Jennifer Durphy

[phone]

Albany

Ana C. Krieger

[phone]

New York

Harini Sarva

[phone]

New York

These are from the RLS Foundation list. I know they have also picked up the names of 50 more doctors at a recent Sleep Meeting and I don't know if they have been added yet, so you could also check back in a couple weeks if none of these are convenient for you at rls.org/treatment/quality-c...

[Truthsword]

Try fasting from glutamate. Its working for me. Here is a link to yhe diet.Allergy diet - glutamate lowaci.health.nsw.gov.au/proje...

Im currently going off Requip after 40 years. Using a little tramadol....none last night.

Wouldnt it be domething if RLS was only an alergy to glutamine!...

Unfortunately, no one will make any money posting a diet.

[Amrob in reply to Truthsword]

How long were you on the diet before you noticed a difference?My RLS is typically mild ((PLMD is the real problem) but the other evening I had parmesan cheese and spinach (which I know are to be avoided on the low glutamate diet). That night, my RLS was off the charts.