supplemental help with RLS?? Anything at all help?

[Camry2020]

any supplements that help with RLS?

[Madlegs1]

I take magnesium citrate 100mg in the evening. It seems to help a bit.

But before anything, you need to get iron levels checked, and look at any possible triggers-- medications or food.

[SueJohnson]

Specifically you need to get your ferritin checked. Do you take any medicines? If so what?

[Camry2020 in reply to SueJohnson]

Only meds are plavix, and rosuvastatin, and pancreatic meds. No DAs, sleep meds or anti depression stuff. Have been on RLS meds for thirty years but not on any now. Don’t know what to do….keep running, but I’m 80 years old and absolutely exhausted!

[SueJohnson in reply to Camry2020]

Rosuvastatin will make RLS symptoms worse. My husband lowered his cholesterol from 221 to 131 by going on a vegan diet.

[SueJohnson in reply to Camry2020]

Why did you come off the RLS meds and what were you on?

[SueJohnson in reply to Camry2020]

I found NEXLIZET which is a cholesterol lowering drug that is not a statin, but don't know if it causes RLS. Might be worth trying.

[SueJohnson]

The site rls-report.com/?gclid=EAIaI... recommends restlex.

[Hidden]

I had a car accident at the end of October, 2021. My calves got jammed really hard against the steering column, with extreme bruising and a large hematoma in one calf. For whatever reason, my RLS symptoms diminished dramatically. I'm telling you this because, I think around the same time, I started taking magnesium. I now take 500 mg of magnesium citrate every night (work up to 500, start on 100 or 200 mg) and the RLS is all but gone. If I get a small flare-up, I take two .25 mg of Pramipexole, and that takes care of the discomfort in less than 30 minutes.

I honestly don't know if the trauma to my legs or the magnesium is responsible for my relief, but it could be the magnesium. Many people take it for RLS. It's worth a try. Magnesium Citrate is supposed to be the best type. I take it at night, with food.

I'm so sorry for what you're going through. RLS is a nightmare. I hope you try the magnesium, and that it helps. Of course, check with your doctor first.

[JasonMorte]

People love to preach about Iron but I've never found any supplement that helped. I don't think it's caused by a deficiency.

[WideBody in reply to JasonMorte]

I don’t think, I KNOW mine was caused by a 10 year iron deficiency without anemia. The clincher was the iron infusion and it’s affect on my RLS and life. “The single most consistent finding and the strongest environmental risk factor associated with RLS is iron insufficiency.”

[JasonMorte in reply to WideBody]

Taking iron supplements will raise blood levels but not necessarily brain levels, which could increase the risk of oxidation from iron overload. For decades we've been advised to avoid red meat for this very reason: too much iron contributes to cardiovascular disease. If indeed low brain levels of iron are to blame, I would advise people to improve their ability to carry iron to the brain by fixing their gut problems. Reduce inflammation in the gut and increase the population of gut flora responsible for uptaking iron.

seratame.com/rls-protocol/?...

[Hidden in reply to JasonMorte]

I think you are absolutely correct. The trillions and trillions of bacteria, yeasts, parasites and viruses that reside in our gut are by in large running the show. The woman in your article seems quite nice and sincere, but naive, as well as her sponsor Seratame - big $$$. She has more chance of winning the lotto and being struck by lightening simultaneously than figuring out the key to a healthy gut microbiome.

There’s only one man who has ever come close (he was a doctor of mine). The biggest influence on gut microbiome, per his research, is our circadian rhythm and following it the way Mother Nature intended. I believe that’s why so many on here have had great success by fasting after an early evening meal and until breakfast. Attached is a glorious, hysterical, fascinating, but long lecture by my doc - Dr. Keshavarzian. He thinks our gut microbiota even influences the way we vote. Please provide a critique if you watch.

m.youtube.com/watch?v=dKSux...(Not working as expected?)

[JasonMorte in reply to Hidden]

Thank you for this link. I'm eager to watch it. Also, the circadian rhythm theory makes a lot of sense.

[DicCarlson in reply to JasonMorte]

Very interesting article and well documented references. The inflammation model for RLS is very compelling. So, the supplements are all available separate from Seratame. Jarrow LP299V, Magnesium Glycinate, and Curcumin 95 (a new concentrated form of Curcumin). Vitamin D3 and K2 should all be available at local pharmacies. I just checked the Jarrow website and the probiotic is ON Sale, free shipping.

jarrow.com/products/ideal-b...

amazon.com/Jarrow-Formulas-...

amazon.com/s?k=curcumin+95&...

amazon.com/s?k=curcumin+95&...

[DicCarlson in reply to JasonMorte]

Did you ever try Seratame?

[JasonMorte in reply to DicCarlson]

I have not tried this product, as these ingredients are all available separately. I started taking curcumin and using kefir.

[HappyGreenBean in reply to JasonMorte]

High iron also raises the risk of some cancers too. There's a lot of reason to be cautious of high iron levels the flip side is not sleeping which contributes to all cause mortality. I don't think it's very easy for people to make a choice other than wanting to rest.

On your point of inflammation. My inflammatory markers are low, very low. And, yet, I have chronic gastritis as well as acid reflux. So, there could be something to the gut being linked, too. But, my diet and lifestyle is what Drs preach. I eat very well, have done for decades and exercise etc. I don't drink or smoke. I'm quite a relaxed person generally, but my ferritin is always low no matter what I do. And, clearly my legs are still an issue.

Interesting stuff.

[grassgree in reply to JasonMorte]

Not everyone benefits from iron supplements. I think the estimate is around 50%.

[JWBe]

I calm my legs using binding agents, which are typically used when chelating toxic metals. My Mercury and Lead were off the chart, with several others significant. My "cocktail" contains charcoal, Microsilica, chitosan, Pectasol C, bentonite, enterosgel and zeolite, mixed in hot water to dissolve. When I feel the RLS come on in the evening, I drink one. Usually, this is enough but sometimes I need another. It usually works very quickly.