Ramipril and Amlodipine and RLS - Restless Legs Syn...

Restless Legs Syndrome

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Ramipril and Amlodipine and RLS

YodaDog profile image
6 Replies

Does anyone know if either of the above blood pressure meds make RLS worse?

Thanks

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YodaDog
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6 Replies

Ramipril is an ACE inhibitor and although I can't be 100% certain, I think it unlikely to affect RLS. It doesn't really affect the nervous system.

Amiodipine is a calcium channel blocker, hence it slows down the action of some nerves/muscles. It does affect nerves and therefore it's possible it may affect RLS. It just depends how selective this is.

Gabapentin, which can relieve RLS also acts on calcium channels (alpha2delta calcium channels), so it is possible that Amiodipine helps RLS.

Otherwise, I haven't a clue!

YodaDog profile image
YodaDog in reply to

Thanks for the reply

dklohrey profile image
dklohrey

I have had RLS for years and have been taking ropinirole. Within the past week I started taking Amlodipine Besylate 5 mg (had been on metoprolol succinate but started having an allergic reaction to it-rash). I have found no difference in my RLS symptoms, either good or bad.

YodaDog profile image
YodaDog in reply todklohrey

Ok, thanks for replying.

Arkangel profile image
Arkangel in reply todklohrey

me too, now on indapamide, helps the heart but no effect on RLS.

YodaDog profile image
YodaDog in reply toArkangel

Thx

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