I am aware of the 2014 study on the efficacy of pregabalin compared to Pramipexole and I remember that one of the findings was that only 2% of those on pregabalin suffered Augmentation compared to 8% of those taking Pramipexole. I am also aware that a member ( I think it was Pam who is also a retired doctor) mentioned that she had augmented on pregabalin after being on it for many years. (I have read that the augmentation symptoms could also have been a progression of the underlying RLS, but the expert doctors were unable to reach any conclusion on this.)
I have a question for all those who have been on Gabapentin or Pregabalin for more that 2 years. Have you experienced a worsening of your RLS or has it moved to other body parts? I ask because I have suddenly started to experience RLS in my arms and hands again- something I last suffered while going through Augmentation on Ropinirole in 2016.
Could pregabalin be similar to dopamine agonists and cause more cases of augmentation the longer you have been taking it? I would be interested to hear from anyone taking pregabalin.
I may try to come off it completely for a few months to see if the RLS in my arms disappears. I am also on Oxycontin so could stay on that.