I have been prescribed Pramipexole to treat my RLS for the last 7 years. My daily dosage is currently 720 micrograms. Even on this dosage the obvious symptoms (leg spasms and discomfort) have begun to occur during the day. Also for the last few months I have spent more time researching the role of dopamine and I think I am exhibiting other symptoms which I previously thought unrelated. These are not limited to: fatigue, compulsive behaviour, depression, anxiety, trouble sleeping and anhedonia. My GP has now agreed to refer me to a Neurologist. Does anyone know what treatment I should expect to receive? I'm really worried that the only treatment available is prescription of 'trial and error' medication.