The first time I took tramadol, after fifteen minutes I felt relief wash over me. It was amazing to sit there and finally have my legs feel normal. I'm beginning to think that's an unfair standard to hold other meds to. I've was on mirapex at .125 mg for five days and now at .25 mg for four days. I'm ready to consider it a bust and move on. Is that too soon? In your experience, how long did it take to get some form of relief from whatever med is currently working for you? Was it hours? Days? Weeks? Months?!