One of the primary symptoms of ME is generalized abnormal muscle fatigue that occurs after relatively mild activity. Fatigue can be defined as a progressive impairment in maximal force generating capacity that develops during muscular activity.
hindawi.com/journals/jar/20...
Objective evidence that the GETSET Trial was doomed as a failure when exercise avoidance and muscle deconditioning were at the core of it's model a hypothesis which ignores muscle and mitochondria dysfunction.