Soursop and causing Parkinsons and PSP

[daffodil48]

I have read quite a few articles on the belief that drinking and eating the Soursop fruit can contribute to Parkinsons and PSP. Tonight I was watching a cooking program and Soursop fruit was an ingredient. Shouldn't the public be made more aware of the dangers of ingesting soursop. Plus I see it is touted as a cure for cancer and other disease ! Cure Cancer but get PSP?????

[honjen43]

What is a soursop?

Hugs

Jen xxx

[abirke in reply to honjen43]

Neurotoxicity

The Memorial Sloan-Kettering Cancer Center cautions, "alkaloids extracted from graviola may cause neuronal dysfunction".[14] The compound annonacin, which is contained in the fruit and seeds of soursop, is a potent neurotoxin associated with neurodegenerative disease,[12] and research has suggested a connection between consumption of soursop and atypical forms of Parkinson's disease due to high concentrations of annonacin.[15][16][17][18] The LD50 of annonacin to dopaminergic neurons is 0.018 uM, which when compared to other known neurotoxins is 100-fold more toxic than 1-methyl-4-phenylpyridinium (MPP), 700 fold more than coreximine, and twice rotenone.[15] Average fruit contains 15 mg of annonacin.[16]

In 2010 the French food safety agency, Agence française de sécurité sanitaire des produits de santé, concluded that, based on the available research findings, "it is not possible to confirm that the observed cases of atypical Parkinson syndrome ... are linked to the consumption of Annona muricata," calling for further study on potential risks to human health.

I took this from Wikipedia.....thank God for Google and wikipedia

AVB

[JR61]

Why would anyone want to eat this after reading the notes related to Health in this link? Ruth x

en.m.wikipedia.org/wiki/Sou...

[honjen43 in reply to JR61]

Agree! Known in this part of the world as 'custard apple'. My understanding is that the toxin isin the seeds. If the seeds are not eaten, does it still contain the toxin?

Definitely not a pleasant neurotoxin!

Jen

[JR61 in reply to honjen43]

Definitely not. I wonder if the incidence of neurological problems is greater in the areas where this is commonly eaten. Certain populations can be affected by the lack of dietary requirements such as affecting the thyroid so it would make sense that they would also be affected by this fruit if they ate the seeds. Not a risk you would take knowingly. Ruth x

[abirke in reply to JR61]

Yes, it is