Hi, my husband has not been offered any medication for PSP, but his condition continues to deteriorate. The complication here is that he had a liver transplant 11 years ago now & still takes an anti viral drug ( his liver was damaged due to hepatitisB) along with anti rejection drugs. He also takes a blood pressure pill & a few others so because the cocktail gets larger & larger I haven't pursued further medication. Do people feel prescribed drugs make enough of a difference that I should pursue this with our doctor ? It's impossible to know how long he has had PSP, but I would say 5-6 years at least. Life has certainly been a roller coaster for 12 years & he is unrecognisable from the man I knew. His balance is very poor now, although he's so determined he manages to look after his daily routine more or less by himself. His speech varies according to how tired he is.