Testosterone

[BadNews4me]

39 sessions of SBRT ended Jan 2020.

HDT ended Feb 2021

Labs Feb 2024: PSA - undetectable Testosterone 283

Would like to supplement testosterone for better QOL. Urologist not helping but primary Dr will help/monitor.

Would like to hear opinions or suggestions both pro & con

[BadNews4me]

Thanks Anomalous, I believe you are correct about lack of sufficient studies keeping some Drs on the bench. I’d be disingenuous if I didn’t say it’s a big step to supplement and I’m a bit nervous about it. But I also want QOL and hope it’s attainable for me without repercussions.

[Tall_Allen]

Many urologists nowadays will prescribe TRT if PSA has been negligible after RP or RT.

[BadNews4me]

Thanks TA. Meeting with doctor today. Any thoughts on how to administer- shots, cream patch?

[janebob99 in reply to BadNews4me]

I've been on testosterone replacement therapy (TRT) for > 10 years (before PCa) because of hypogonadism. I've taken both cream and gel...both are good. Today, I get it from a higher concentration (than Androgel) from a compounding pharmacy. You may want to ask your Primary Care Physician for a prescription to a compounding pharmacy. Australia also sells a T-creme that is popular. The shots have a much higher Peak/Trough cycle than daily cream/gel, plus they are a pain in the a**.

Also, check out the papers and YouTube videos by Abraham Morgentaler from Harvard. He's published over 170 articles about testosterone. He proposed the testosterone saturation model, where T-levels above 250 have no effect on PSA and no additional incidence of PCa, which has been experimentally validated. The explanation is that the Androgen Receptors (AR's) have become saturated with Testosterone (actually, DHT), and can't respond to any additional amounts of T (DHT). He's also written about the safety of doing TRT with prostate cancer. Most of his papers are from around 2016.

Bob