What is "high volume" GL 6? - Prostate Cancer N...

Prostate Cancer Network

5,158 members3,240 posts

What is "high volume" GL 6?

witantric profile image
16 Replies

I was watching Dr. Klotz's video on AS. He mentioned that people with "high volume GL 6" should reconsider AS. What exactly is high volume GL 6? He never defined it.

Written by
witantric profile image
witantric
To view profiles and participate in discussions please or .
16 Replies
Tall_Allen profile image
Tall_Allen

It's what I had. A lot of cancer, all GS6.

witantric profile image
witantric in reply to Tall_Allen

How many cores with cancer?

Tall_Allen profile image
Tall_Allen in reply to witantric

I forgot exactly- more than half the cores, and a lot of the cores were cancerous

marnieg46 profile image
marnieg46

Did you get a chance to watch the podcast? A couple of the doctors were from the States and one from Vienna I think?

Teacherdude72 profile image
Teacherdude72

Just as it says: high volume means big.

adventure4me profile image
adventure4me

I have the same question, have watched Dr. Klotz and had exactly the same uncertainty. I have 8/12 systemic cores plus 4/4 targeted cores positive G6. (80%,30,30,30,20,20,20,15,10,10,10,5%). Am I "high volume", and am I a good candidate for AS?

witantric profile image
witantric in reply to adventure4me

Others can chime in. But that seems high volume. What did your urologist say?

witantric profile image
witantric in reply to adventure4me

Also, did you get any genetic testing done?

adventure4me profile image
adventure4me

Urologist said it's high volume and suggested either AS (despite high volume), RP, or Radiation and referred me to RO and UO. Have met with (2) RO, both kind of said surgery is better for me due to young age and AUA score 20-25. One seemed to lean toward AS, the other toward surgery. However both RO were very much offering options, thoughts, and information and made it clear that it's my decision. No genetic testing done. Will be chatting with (2) UO in coming weeks.

Really could argue for any of the three it seems, we're still gathering info from Dr and online, not rushing to a decision.

thx for the replies

witantric profile image
witantric in reply to adventure4me

All good options. Just be vigilant.

NYC_talker profile image
NYC_talker in reply to adventure4me

Your young age should not drive you to surgery. This is a common misconception and too often pushed by surgeons. Equal outcomes with radiation or surgery but the side-effects short term, and possibly long-term are worse with surgery. Please read some of Tall_Allen's posts and articles on his website.

j-o-h-n profile image
j-o-h-n

Remember what your Mom used to say to you..... Henry!!! Don't be such a Klotz.....

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 03/29/2023 7:45 PM DST

addicted2cycling profile image
addicted2cycling in reply to j-o-h-n

Gee, my MOM and her MOM (Grammy) always said to me to "Go take a LONG WALK off a short pier." glug-glug

j-o-h-n profile image
j-o-h-n in reply to addicted2cycling

Mine said "walk till your hat floats"...........

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 03/29/2023 10:24 PM DST

TFU589 profile image
TFU589

Just listened to podcast on Dr. Geo Espinosa's website on Active Surveillance . He interviewed a Dr. Aditya Bagrodia, he is a urologist at UCSD. He was asked to give his definition of "high volume". His answer was "more than 6,7,8 positive cores. More than 50% positive cores, and both sides."

podcasts.apple.com/us/podca...

witantric profile image
witantric in reply to TFU589

Thank you, sir. Very useful

Not what you're looking for?

You may also like...

Post -OP PSA is 5.01. What Questions do we need to ask when we meet with the Doctor?

Husband's RP was 1/7/22. Pathology report said margins were not clear, tumor had broke outside the...

What is the best threadmnt for Gls7 on T1?

Hi...i'm new..sory for bad english.. My father just got Pca last mont.. Last mont psa 5.6 (with...

How to determine what is a normal PSA after radiation therapy?

As I understand it, when PCa is treated with radiation therapy, the theory is cancer cells are more...

Newly Diagnosed Prostate Cancer

Thank you in advance for your inputs. - Most recent PSA was 7.82 (Sep 2021)(rose from 3.0 over last...

Is high protein safe?

I'm 51, Gleason 6, and my PSA has ranged from 5.5 to 9.2 over the past year. I get a PSA test...