The only times I ever hear patients regret the initial treatment decision (whether prostatectomy, radiation, active surveillance, or ablation) is when they didn't take the time to investigate all their options before deciding. Even very high risk prostate cancer (non-metastatic) is slow to progress. There are now several studies that show that men who rush to treatment do no better than men who delay treatment for many months. I just updated this article with the latest studies:
I also believe that we make more rational decisions after we have taken the time to let our emotional temperature come down.