Gastro resistant tablets

[LadyJayne68]

Hi, when I was given Prednisolone in August they were the standard tablets and I was given Omeprazole 'to prevent stomach ulcers'.I have read about gastro resistant tablets. Would these be better or would I still need the Omeprazole? Thanks 🙂

[SnazzyD]

I had gastro resistent Pred because I couldn’t tolerate Omeprazole and its relatives and the alternative didn’t work after a while. Changing to enteric coated Pred was a game changer but I still needed some Gaviscon at bedtime. If you do swap, don’t forget you can’t just stop Omeprazole but must tail it off to avoid rebound acidity.

[LadyJayne68 in reply to SnazzyD]

Oh thank you, I will remember that.

[Kendrew]

Hi there,I've taken gastro-resistant pred for 5½yrs and refused a PPI until such a time as I have evidence (symptoms) of requiring one. So far I've not needed a PPI!

We're all different though and you must decide what's appropriate for you.

[piglette]

I also had gastro resistant tablets and took nothing else to protect my stomach, although I did take them with plain yogurt.

[LadyJayne68 in reply to piglette]

Am I right in thinking the non coated ones are easier to cut as the dosage changes?

[PMRpro Ambassador in reply to LadyJayne68]

You can't cut the coated ones - if you use some coated, you can make up the dose with plain ones and for some people that is enough to reduce gastric irritation. I used both in the UK and found that making up a total dose with only 2 or 3 plain 1mg tablets was fine but with 4x 1mg tablets I felt this little rodent nibbling away in my tum!! Strange that such a small amount made a difference. So I had 5 and 2.5mg coated ones and never needed more than 2x 1mg plain which was absolutely fine.

[paintpots]

I was given omeprazole when I was first given pred. It took 4 years to clear the pmr and come off pred but 5 years later I seem unable to come off the omeprazole, I have to take a tablet at least weekly. It is difficult to get off it.

[LadyJayne68 in reply to paintpots]

😞

[Lagnershan]

I take Omaprazole 10mg/day to reduce acid reflux. That problem started some years ago when I had my gallbladder removed. Now since PMR I take 9mg of Prednisolone and have not had any noticeable side effects. Without the Omaprozole, I have severe acid reflux and yellow diarrhoea.