Anyone tried LDN to taper?

[MalloryMoss]

Hello

Has anyone tried Low Dose Naltroxene (LDN) to taper off Pred? I have tried searching and can find info on LDN on Health Unlocked generally, but wondered if anyone has used it on this forum. Thanks

[DorsetLady PMRGCAuk volunteer]

Now you have asked, you can see related posts. Top on list from papadapadoo is quite interesting

[MalloryMoss in reply to DorsetLady]

thank you!

[SnazzyD]

Now you’ve put it in your title, you should now see other posts about using LDN. As you can see it has come up before, happy reading!

[MalloryMoss in reply to SnazzyD]

thank you!

[PMRpro Ambassador]

Been discussed a few times - and my daughter who uses it (not for PMR) says there are loads of PMR patients on her forums.

[MalloryMoss in reply to PMRpro]

thank you

[Hopeful424]

Actually, I did try it and did not get a significant response. I may not have used it long enough. As each person is different, I would give it a try. Very little, if any ,side effects to this usage at low dose.

[MalloryMoss in reply to Hopeful424]

Thanks, I’m going to give it a go. Will report back

[Catsrcool]

I did try Naltrexone 1.5mg then was to increase until I reached 4.5mg but it made my fatigue worse, so I didn’t continue using it.

[MalloryMoss in reply to Catsrcool]

That’s interesting thank you, I have no fatigue at all so will see how it goes.

[Wizards]

There were a couple of us 7-8 yrs back going to try it. I gave my GP the information and he gave me a prescription however was trying another new drug which worked so never started it.The other 2 I believe ended up starting it and dropped it because it didn't make a difference.

We are all of prednisone now.

[MalloryMoss in reply to Wizards]

ok thank you, good to hear you're off Pred now!

[Altpmr]

I take 4.5 mg LDN nightly, and tapered methyl pred extremely slowly. No longer on steroids. I also receive 25g vitamin C and 2 g Magnesium via IV weekly. Sed rate and CRP are nearly undetectable. Took a couple of years to taper, but no longer dependent on steroids. Note that LDN may cause you to have vivid dreams at the beginning.

[MalloryMoss in reply to Altpmr]

thank you for this, very interesting. How long have you been free from Pred? and what did your taper look like i.e. 1mg each month or slower? thank you

[tracesoflove]

Yes, I used LDN while tapering and it worked for me--worth the try.

[MalloryMoss in reply to tracesoflove]

That's great to hear! how long did it take and what dosage Pred were you when you started taking LDN?