MGUS gone!

[Karenjaninaz]

When I was first diagnosed with PMR 2015 MGUS was found. Last week I consulted a respected, experienced hematology oncologist. Had a raft of tests. I also saw the results on my patient portal. The abnormal protein was not found. I asked the doctor how many times this happens in his extensive practice. He said “a couple of times a year”. He said it can come from a number of things: inflammation and illnesses.

His recommends coming in next year for the bloodwork, as it can come back, though I was low risk before.

[PMRpro Ambassador]

That's great - and long may it last!!!

[pata63]

That's interesting to hear, and as PMRpro says, long may it last.

My GP had extra analysis done on my recent bloodwork because I have started to have peripheral neuropathy and a few other odd symptoms I haven't had before in my time with PMR (since mid 2018) and GCA (dx June 2024). On 10-Sep-24 a paraprotein (IgG lamba) at 3 g/L was found. First I had ever heard of MGUS, but of course now that I've heard about it I've found there are a few of us who have it. But I haven't heard of it going away before. Only an uncertain estimate of 1% to 2% per year progression to myeloma. Going away by itself does seem to fit within the general uncertainty and strangeness of MGUS.

I've got an appointment with a specialist diagnostician in early December to have a look over all of my medical history to help make sense of things and decide what next. From my reading of the technical literature so far I expect "what next" for MGUS will be annual extra analysis for paraproteins when my bloods are done. Watch and wait seems to be the general strategy.

[Karenjaninaz in reply to pata63]

I will be going back next year for a recheck.