duloxetine : Hi - has anyone been put on duloxetine... - PMRGCAuk

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duloxetine

Glutusmaximus profile image
22 Replies

Hi - has anyone been put on duloxetine

My consultant put me on it last week not sure what it is for I know it’s an antidepressant which I suppose I need to cope with the not knowing why I’ve been hurting so much.

has anyone noticed it helped with anything else. after a couple of days I noticed my knees not stinging so much a little less sore but they felt numb and still do it’s a weird feeling.

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Glutusmaximus profile image
Glutusmaximus
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22 Replies
DorsetLady profile image
DorsetLadyPMRGCAuk volunteer

No experience, but it can be used for some pain not only as an antidepressant, think it depends on dosage used, just found this on a very quick search - and it probably says similar in Patient Information Leaflet -

"Duloxetine is also used in adults to treat nerve pain caused by diabetes (diabetic neuropathy), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain).

Some brands of duloxetine are also used to treat fibromyalgia (a chronic pain disorder). Drizalma is for treating fibromyalgia only in adults. Cymbalta may be used to treat fibromyalgia in adults and children at least 13 years old."

Glutusmaximus profile image
Glutusmaximus in reply toDorsetLady

Thank you 😊 I had my blood tests done today so hopefully get the pred to trial as still in so much pain at night . I’ve been trying to do my exercises in hydrotherapy pool this week and a little swim but I get cramp in my feet ☹️ and my lower back has been so sore

DorsetLady profile image
DorsetLadyPMRGCAuk volunteer in reply toGlutusmaximus

Hope they soon try you on Pred. My GP prescribed Amitriptyline [another antidepressant used for pain like Duloxetine] before my GCA was diagnosed…did diddly squat for me!

Glutusmaximus profile image
Glutusmaximus in reply toDorsetLady

That made me feel Awful I had terrible nightmares and felt so bad in the mornings on amitriptyline and norotriptyline ☹️ at least at the moment no side affects from duloxetine and I’ll push for the pred soon as I get my report bk from my bloods. I am waiting to see another rheumatologist for second opinion but maybe my endocrinologist will find something out first as he was the one that said about PMR it’s just my doctors won’t do a ERS test!

DorsetLady profile image
DorsetLadyPMRGCAuk volunteer in reply toGlutusmaximus

👍

suzy1959 profile image
suzy1959

I was on duloxetine briefly in the summer. This was partly to test my Rheumy's theory that I have Fibro and partly to see if it would help my sleep ( like Amitriptyline) or my pain.

It didn't help anything and made my sleep worse!

Glutusmaximus profile image
Glutusmaximus in reply tosuzy1959

I have noticed I can’t get off to sleep so easy so I started taking it earlier I am still in pain especially at night and stiff first thing in the morning it takes at least an hour or so to loosen up

piglette profile image
piglette

Duloxetine will be no use if your consultant thinks you have PMR. In that case you need to have a trial of steroids for a week or so and see if you have magical results. Perhaps your consultant thinks you have fibromyalgia?

Glutusmaximus profile image
Glutusmaximus in reply topiglette

Consultant said 2 yrs ago it wasn’t fibro but then again she said it wasn’t the mild OA in my left hip and right knee causing it either pretty useless tbh I’m waiting on seeing another consultant but my dr will do pred trial I have an appointment on the 31st to see her 🙏🏼

piglette profile image
piglette in reply toGlutusmaximus

That would be great if they could do the pred trial. At least it can remove (or not) PMR as the diagnosis for very little cost.

Glutusmaximus profile image
Glutusmaximus in reply topiglette

Yes I still have to pay the consultant to read my resent tests I had done yesterday though ☹️ but my dr did say we could try pred for a week see if it does help I hope she keeps to her word as I know when I was on them last year twice for chest infection that they eased my aching legs . I have had bursitis in both shoulders for going on two years now and just been diagnosed with moderate OA in right acj joint ☹️

piglette profile image
piglette in reply toGlutusmaximus

Hope you get the steroid trial. Let us know the result.

Glutusmaximus profile image
Glutusmaximus in reply topiglette

Thank you - I hope so too and I will definitely let you all know 😊

Moonshine15 profile image
Moonshine15

Good morning I have been on Duloxatine for for a few years, it’s an antidepressant but also licensed for peripheral neuropathy which is what I take it for.

I don’t suffer from any side effects but I can’t say it takes the pain away completely, however I came off it once and the pain was worse so it’s doing something.

I hope it works for you

Glutusmaximus profile image
Glutusmaximus in reply toMoonshine15

Thank you for the reply yes I have no side effects I can say I’m slightly more comfortable but still sore in my knees and shoulders and can’t lie on either hips during the night the pain is waking me ☹️

Pixix profile image
Pixix

I tried it for fibromyalgia & osteoarthritis…but I was so sick…my balance was worse…I felt like I’d drunk a whole bottle of wine…& did I mention sick? Only managed 4 days! But some gain relief from it & it works well!

Glutusmaximus profile image
Glutusmaximus in reply toPixix

Hi sorry to hear you had side effects on it I had those on amitriptyline it was awful

Pixix profile image
Pixix in reply toGlutusmaximus

Ha ha, you understand then, thanks! But I can take one Amitryptyline each evening as a muscle relaxant & no side effects at all! Take two Amitryptyline & I don’t get up until noon!! I’m sorry you had the problem! S x

Glutusmaximus profile image
Glutusmaximus in reply toPixix

Yeah I tried amitriptyline and then the rheumatologist said try noratriptyline as you won’t get the same reaction but I did and you’re right you feel groggy I used to get terrible nightmares too horrendous feeling . I’ll keep going with the duloxetine and see how I am when on pred trial I just can’t wait to see some results and not constantly hurt.

My rheumatologist said it was stress!! and I think this not being diagnosed is what has caused the stress being unwell for so long and not knowing what is wrong with me has been hard it starts to make you think is it all in my head - but when I wake up crying out in pain well I know it’s not but they just didn’t want to listen

Pixix profile image
Pixix in reply toGlutusmaximus

Oh, yeah??? Stress? Not necessarily, I would say to that! I get nightmares nearly every night. They are very vivid indeed & sometimes I can remember all the details in the morning . They’re always impossible, twisted, nasty, & sometimes I’m in my old job trying to achieve the impossible! Hope you get a diagnosis soon. You’re right, once you know then you can face it. But perhaps they don’t know?? S x

Glutusmaximus profile image
Glutusmaximus in reply toPixix

I’ve been off work since February really bad flare off balance seevere muscle joint pains! Yes I had stress at work being bullied because I was different in what I could do but it all mounted up and then bang! Downward spiral to Rock bottom all I’ve done for the last 7/8 months is chase hospital/ doctors and work meetings about my health..

I wish I could work FT and earn a decent living but I can’t I went from 30 hrs down to 22 last June after a bad time now I don’t even think I could manage that when I return if they’ll have me back or try and get rid of me that’ll be the next thing incapable of doing my contract hours ☹️

Pixix profile image
Pixix in reply toGlutusmaximus

Rotten luck. I should push them for a definite diagnosis, if you can!

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