Use by Dates and Prednisolone

[Kendrew]

I have a prescription of unopened 1mg gastro-resistant Prednisolone tablets.

They've been kept in a cool, dry place but the expiry date is Oct 23.

There seems to be mixed opinions from my research online as to whether you can continue to use Prednisolone after the expiry date, and for how long after too.

I would appreciate any thoughts regarding the following please:

- Can you take Prednisolone tablets after expiry date?

If so:

- How long after the expiry date are they okay to continue using?

Thankyou

[DorsetLady PMRGCAuk volunteer]

Hi.

There are related posts, but I think general consensus of opinion is use common sense, if they are only just out of date or even a few months they’ll be okay… but much longer than that and it probably isn’t.

Not that they would do you any harm as such, but that they might not be as effective as they should be.

But one pack of tabs, even GR isn’t that expensive, so don’t feel guilty about throwing them away…that’s what the pharmacy would do if you returned them.

[Kendrew in reply to DorsetLady]

Thanks DL.

[ypanfileee in reply to DorsetLady]

As a professional I don't recommend taking any drug after the expiration date

[PMRpro Ambassador]

Well I would use those up now - they don't self-destruct overnight at the end of October!!!!

[DorsetLady PMRGCAuk volunteer in reply to PMRpro]

🤣😂

[Kendrew in reply to PMRpro]

👍👍👍Thanks

[Greensleeves]

Hello lovely Kendrew ,

I think they’re fine for a good few months. The pharmacist told me he couldn’t comment but went on to say , with a wink , they’re sending out of date medication to the Ukraine . Plus our military use outdated meds such as antibiotics.

It’s good to have a spare supply in too .

Take care xx

[DorsetLady PMRGCAuk volunteer in reply to Greensleeves]

..they’re sending out of date medication to the Ukraine .Plus our military use outdated meds such as antibiotics.

That’s sounds about correct -but it doesn’t make it right.

[Greensleeves in reply to DorsetLady]

I agree DL , it doesn’t make it right at all , they’re not inferior to U.K. citizens and our military deserve first class treatment.

I think he was implying they’re safe for several months.

[Kendrew in reply to Greensleeves]

Thankyou ❤

[piglette]

I know that Dr Ben Oldacre in Bad Science said that the majority of drugs will last a lot longer than their sell by date provided they are kept in a dark, cool area. He did say there were a few that you should not take, but they tended to be ones which were in liquid firm and needed to be kept in fridges.

[Kendrew in reply to piglette]

Thanks piglette.

[Smithie49]

Hi Ken drew. When I first experienced PMR symptoms , the GP wouldn't prescribe pred as my blood results were within normal range. In desperation I took 10mg of pred that had been prescribed for a 2 Yr old and were 4 yrs out of date!!! That night I could move without pain or stiffness for the first time in weeks. So I'd say 'yes' - out of date pills still work 😀

[Kendrew in reply to Smithie49]

Thankyou

[herdysheep]

I was recently given some with the Oct expiry date. It may be that after a time when supplies were low, new orders were over the top. I worry slightly that when you are on lower doses, the impact of less oomph may be more noticeable but at least we have got them!

[Kendrew in reply to herdysheep]

Thankyou.👍

[Gimme]

The expiry date tells you how long the manufacturer has stability data for and how long they can guarantee that the content is still safe and efficacious. All drugs degrade over time, which means they may become less effective and in a few drugs, the breakdown products can be toxic. And has been mentioned, liquid products may no longer be microbiologically safe. However, many drugs are fine for long after the expiry date and if the stability studies are still ongoing, it is not unknown for the shelf life to become extended from 3 years to 5 years, for example, during the life of the product. I would have no qualms about using your pred that expires in Oct 23, but if it were me, I would use that pack first before opening a new pack.

[Kendrew in reply to Gimme]

Thankyou...yes, I'm using the pack in question. By doing this I can maintain some spare tabs for 'emergencies' as my other bottles have a 2025 expiry date.

[AshPen9]

I've got some of those October 23 1mg tablets too Kendrew! I don't think they make them too often. I had several tubs of them with that date.

[Stills]

Off topic a bit….. I get two different creams for different things on repeat script. One gets used over a very wide area and the other over a tiny tiny area and one tube lasts a year and usually expires before being used up (I continue to use it). Anyway despite the different application of each both tubes are prescribed the same size which makes me laugh as one tube hardly lasts a week and the other expires! I’ve told them but to no avail and luckily I can buy one from the pharmacy however it’s very expensive

[Temeraire]

I was told by Pharmacy that expiration dates are always end of the month given. Hence 31st October. However I would personally use them for a few weeks past that date happily.

[Bramble2000]

It will be fine. X

[Lochy]

I discovered my next tub I was about to start has exactly the same expiry date so you’ve just answered my question for me! I’ll use them anyway.

[PMRpro Ambassador in reply to Lochy]

If I remember rightly - the last time there was a shortage of 1mg enteric coated pred, when the new batch came out it had an expiry of October 2023. They are obviously clearing stocks. These batches are only made when required as the demand is fairly low - hopefully they are in the process of setting up a run!

[Sharitone in reply to PMRpro]

Yep, the ones I got today expire March 2025. seem to be done every 18 months.

[PMRpro Ambassador in reply to Sharitone]

Thank goodness!!

[Blairrs]

Yes, generally, a minimal expiration date breach is not critical, especially if the medication has been stored properly in a cool, dry place. While it’s always best to adhere to the expiration date, many medications, including Prednisolone, may still be effective and safe for some time after that date, but their potency could decrease. If in doubt, it's wise to consult with a healthcare professional.

I’ve used Prednisolone myself, I ordered it from a reliable pharmacy here - global-world-delivery.com/c... and it worked well for me. It significantly helped with my symptoms, and I didn't experience any issues during treatment. However, if you're unsure about the expiry, it's always safer to get a fresh prescription.

[PMRpro Ambassador in reply to Blairrs]

Did you notice this post is over a year old?