I want to stop omeprazol after 25 years of use - PMRGCAuk

PMRGCAuk

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I want to stop omeprazol after 25 years of use

tophill profile image
36 Replies

I am on Omeprazole more than 25 yrs. I want to stop it but when I omit to take one 20 mg pill I could not sleep at all. Can any one else have this experience? I would be so thankful, for any information because I feel that I am in a dark place, and bad mood.

Thanks a lot in advance.

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tophill
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36 Replies
SnazzyD profile image
SnazzyD

What symptoms did you get that made you not able to sleep?

tophill profile image
tophill in reply to SnazzyD

I did not have any symptoms just I couldn't sleep it is like a sleeping pill that I forgot to take. Its insomnia. When I took a 20 mg omeprazol I managed to sleep without problem every night as usual.Thanks a lot for your reply

PMRpro profile image
PMRproAmbassador

Is it acid reflux keeping you awake or something else? It is said that withdrawal of omeprazole leads to many adverse effects including insomnia.

Instead of not taking a tablet at all - try taking 10mg instead and see it that helps. Then very slowly increase the number of days you take 10mg instead of 20mg. If that works you are at least on a much lower dose. Then if that has worked - introduce odd days of no dose in much the same way.

But it is possible you need something - maybe switching to famotidine or cimetidine will be required to stop the PPI,

You may find this interesting or helpful

menshealth.com/health/a4306...

tophill profile image
tophill in reply to PMRpro

Thank you very much. I am a Greek and here there are notpills 10 mg. The two medicines you sugested me if possible what is the brand name of them? I could find them more easily. My best wishes for good health.

PMRpro profile image
PMRproAmbassador in reply to tophill

Famotidine is sold as Pepcid though there may be other names. Cimetidine is Tagamet - again, there may be other names. Is it pills you have? If so, you can probably cut them. Capsules can be opened and some of the contents removed. But a pharmacist can always tell you brand names if you know the substance name,

tophill profile image
tophill in reply to PMRpro

Thanks again for the useful information. Yes, I take every day a pill 20 mg and some times 40 mg. now I will discuss with the oharmasust about your suggestions. I will try to minimize the quantity of drastic substances as you told me. Best wishes

Hoofprints profile image
Hoofprints in reply to PMRpro

Would it be ok to PM you?

PMRpro profile image
PMRproAmbassador in reply to Hoofprints

You don't have ask - no-one else does!!!!

tophill profile image
tophill in reply to Hoofprints

Sorry but I don't understand whatyou mean, if it possible tell me ìt

With other words

My English is too poor. Anyway

thanks a lot

PMRpro profile image
PMRproAmbassador in reply to tophill

Hoofprints was asking me a question. You were notified because you started the thread but Hoofprints clicked on Reply to my comment and it says next to my nake it is directed at me.

tophill profile image
tophill in reply to PMRpro

OK PMR pro thanks very much for explanation otherwise would

be a misunderstood for me

bb and have always a good time

Nanatoo profile image
Nanatoo

I didn’t like the side effects of omeprazole 20mg constipation wind so gp changed me to Lansoprazole 15mg which seemed to have the same effect. I’d only been taking ppi’s for 2 months so thought I’d just stop taking anything but got terrible burping episodes and bloating so think I’ll start taking it every other day for a while to see how that goes.

tophill profile image
tophill in reply to Nanatoo

Hello nanatoo. I thing you are doing very well to take day after day. So the side effects will be less and after that try to stop it. Best wishes

HamishPMR profile image
HamishPMR

Then why stop? There is no need to.

tophill profile image
tophill in reply to HamishPMR

Hello HamishPMRI had a lot of problems with my stomach. After many years l manage to control them. Now I feel well and I think is not necessary to take this pill. That's why I try to stop it but as I see is very difficult, and every experience from others would be very useful.

HamishPMR profile image
HamishPMR in reply to tophill

Omeprazol was been on the market for a long long time with very very few problems so why stop taking it when it helps?

tophill profile image
tophill in reply to HamishPMR

Hello PRMI had little side effects but besides I have a serious side effect. My hematocrit was 45

and now is 38,5, may be and other reason, but blood test

is normal. I hear that some other people had the same side effects. Anyway the les pills the better health. I try but I don't know for sure the rezalt

Thanks a lot ant wish to be always well

Karenjaninaz profile image
Karenjaninaz in reply to HamishPMR

These proton pump inhibiters have been associated with dementia.

tophill profile image
tophill in reply to Karenjaninaz

Hello KarenaninazWhat you say I hear from many

people and this make me to fear

but some times you must take them. i imagine you are young

and you haven't any such problems I wish from deep Heart to be always in good Health

Karenjaninaz profile image
Karenjaninaz in reply to tophill

I am 81 retired medical professional. I also needed to take such drugs in the past; now these give me wind. I take a safer alternative when needed.

tophill profile image
tophill in reply to Karenjaninaz

Thanks again and your reply boost my good feelings and hope about Omeprazole. Best wishes

AyJayBass profile image
AyJayBass in reply to Karenjaninaz

Karenjaninaz - are you able to provide links to any medical papers that support the theory that proton pump inhibitors are associated with dementia please?

PMRpro profile image
PMRproAmbassador in reply to AyJayBass

news-medical.net/news/20230....

The reference to the actual paper is at the bottom of the summary

AyJayBass profile image
AyJayBass in reply to PMRpro

Thanks

Karenjaninaz profile image
Karenjaninaz in reply to AyJayBass

pubmed.ncbi.nlm.nih.gov/329...

AyJayBass profile image
AyJayBass in reply to Karenjaninaz

Thanks Karenjaninaz. I noted "Conclusions: This study, using large-scale, multi-centre health-data was unable to confirm an association between PPI use and increased dementia risk. Previously reported links may be associated with confounders of people using PPI's, such as increased risk of cardiovascular disease and/or depression and their associated medications which may be responsible for any increased risk of developing dementia."

Karenjaninaz profile image
Karenjaninaz in reply to AyJayBass

There are many studies, other than this, suggesting a link.

This is anecdotal: My aunt had a successful cure of stomach cancer by partial stomach removal. I guess, for reflux, she was prescribed Nexium, which she took about 20 years,

.She took, BP meds, was normal weight, non smoker, light drinker. She developed dementia in her 80s. She died in a facility at age 91.

My mom, her sister, on similar meds,( after poor BP control ; she was afraid if doctors ) was actually less healthy but never took a PPI. She was sharp as a tack until her death at 93.

I am convinced it was the PPI’s.

PMRpro profile image
PMRproAmbassador in reply to AyJayBass

Bit of mixed messages in that paper methinks ...

Karenjaninaz profile image
Karenjaninaz in reply to PMRpro

Yes, you are right.

I haven't searched any further for additional studies but I notice clinicians are not so eager to prescribe PPIs, long term, as in the past.

paintpots profile image
paintpots

I have been on several prazoles since I developed pmr 4 years ago. They all upset my stomach so a year ago I decided to stop them but I had bad indigestion so I have done a slow taper and now only have a 15mg tablet perhaps once a week or less now, depending on if the indigestion has come back. I am on .75mg of pred now so I think the need for a prozole is not so great.

tophill profile image
tophill in reply to paintpots

Paintpots, I greet you and I see the effort you done and I think you àre in a better stateI wish every effort to have good and.

Pr0jection profile image
Pr0jection

Although I haven't had such a bad experience with omeprazole I wasn't happy taking it long term for diverticulitis and gastritis. Instead I switched to taking probiotics and drinking goat's kefir. I take 3 probiotics a day and 3 sips of kefir. Last week I wondered if I could cut down to 2 probiotics per day. Within 2 days my 'old' problems were back so I went back up to taking 3 a day and now I'm fine. This might not be of any help to you, just my own experience. I wish you good luck....

tophill profile image
tophill in reply to Pr0jection

Hello ProiectionI would like to know the equal quantity in ml or grammar. Best wishes

Pr0jection profile image
Pr0jection in reply to tophill

Hi tophill, it's best if I give you details of where I buy the probiotics and then you can investigate. It's healthspan.co.uk - search for probiotics. With regard to the goat's kefir I buy a 330ml of natural probiotic goat's kefir and take about half a 'shot' glass 3 times per day. I keep 3 bottles in the fridge at any one time. Good luck....

tophill profile image
tophill

Thanks a lot projection

Stills profile image
Stills

I sleep badly, always have, 4 hours usually, 6 would be excellent. I’m usually med free apart from pain relief but these last months have been on omeprazole for undiagnosed something or other, tests on going. Started on 40 for 2 months then 20 for 2 months then one month 20 alternate days. Two months after cessation symptoms returned so now back to 20 daily. It has not helped my sleep in any way but has reduced trips to the loo in the night ( interstitial cystitis ) which is an unexpected benefit. I listen to Gregorian monk chanting which is soothing. Wishing you better nights,

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