prednosolone + aspirin+ amoxicillin

[Ushern]

ibe been having stomach and back pains for some time now .. used to be temporary first times lately have been frequent, so I went for check up did some test there including urinalysis.. Didn't find anything wrong. so they prescribed me with amoxicillin prednisolone and aspirin toldme I have to take a lot of liquids...is the drug combination safe to take altogether?

[PMRpro Ambassador]

The mix is considered safe - but I suspect you MIGHT bruise easily for a few days. Though if they didn't find anything - why give you an antibiotic?

However - we are just patients so you really should discuss it with a doctor if you are worried about it.

[DorsetLady PMRGCAuk volunteer]

I took Pred and aspirin (already on pre GCA diagnosis) with no issues....and also an antibiotic early days for oral thrush..

[SheffieldJane]

Have they done any pelvic investigations? Pelvic congestion can give rise to your symptoms. Dragging pains, particularly towards the end of the day. IBS and or Urinary symptoms. Back and lower abdominal pain, bloating.What is the aspirin for? The combo seems safe but as a fellow sufferer - odd.

[Exflex]

I’ve had all three together without any known issues. I take aspirin 75mg and have for over 12 months, continuing until I pop my clogs. Pred because of PMR and amoxicillin on four separate occasions this year due to a problematic tooth. I have no apparent issues with the combination, apart from bruising easily, esp the hands.

[MrsNails]

There’s a Post on Drug Interactions in FAQ’s (U.K. Access Only)

healthunlocked.com/pmrgcauk...

I always cross check myself but my GP’s pretty good - but l think that’s because the Screen Flashes with a Red Warning as l’m on MTX

It’s always worth checking & reminding the Dispensing Pharmacist too….

[DorsetLady PMRGCAuk volunteer in reply to MrsNails]

Nothing on profile to say where from -defo not PMR patient at 24! Only joined yesterday so probably found us by default on the Pred tag…

[MrsNails in reply to DorsetLady]

Ah, l did wonder about prescribing of Prednisolone…….

[DorsetLady PMRGCAuk volunteer in reply to MrsNails]

He got answers, so guess that that’s main thing -but it would be nice for a simple thank you….Or am I too old fashioned?

[PMRpro Ambassador in reply to DorsetLady]

Probably ...

[DorsetLady PMRGCAuk volunteer in reply to PMRpro]

Brung up properly -like you!

[PMRpro Ambassador in reply to DorsetLady]

I'd agree ...

[Charleees]

Hi! I understand your concern—it’s always good to double-check when taking a combination of medications. First, I’m not a doctor, but I’ve taken amoxicillin before for a sinus infection, and it worked really well for me. I ordered it from trusted pharmacy here: global-world-delivery.com/c.... It's a widely used antibiotic, so if it was prescribed for you, it’s likely addressing a suspected bacterial issue.

Regarding your prescribed combination of amoxicillin, prednisolone, and aspirin, these can typically be taken together, but there are a few things to keep in mind:

Amoxicillin: It's usually safe, but if you're allergic to penicillin, let your doctor know immediately.

Prednisolone: This is a steroid and can irritate the stomach lining, especially when taken with aspirin. Taking it with food can help reduce stomach discomfort.

Aspirin: While it’s great for reducing inflammation and pain, it can also irritate the stomach. Since you're already experiencing stomach pain, make sure you’re taking it as directed and with plenty of water or food.

Your doctor’s advice about drinking lots of fluids is spot on—this helps with any potential irritation and supports your overall health. If you notice any side effects like worsening stomach pain, nausea, or unusual symptoms, reach out to your healthcare provider right away.

Hope this helps, and wishing you a speedy recovery! 😊