Anyone with any understanding of likely interactions?
As I am also on MTX (Methotrexate), an immunosupressant, I wonder if I am more at risk or less at risk from Covid19?
Found this:
thelancet.com/journals/lani...
"Such drugs are predicted to be of particular importance in the treatment of severe cases of COVID-19, when the host inflammatory response becomes a major cause of lung damage and subsequent mortality. " ............"The most significant side-effect seen over 4214 patient-years in the clinical trial programmes used for European Medicines Agency registration was a small increase in upper respiratory tract infections (similar to that observed with methotrexate), but the incidence of serious infections (eg, herpes zoster) over 52 weeks' dosing was small (3·2 per 100 patient-years), and similar to placebo.7 Use of this agent in patients with COVID-19 over 7–14 days, for example, suggests side-effects would be trivial."
...which might be saying that a drug such as MTX reduces lung damage????? ...or does it mean something entirely different?
Meanwhile in Iceland......
"Q. Who is at risk for severe symptoms? A. Risk groups for severe infection have not been well defined. Most people who died in the early phase of the epidemic were elderly and suffered from chronic conditions, such as heart disease or high blood pressure, lung disease, diabetes or liver disease. At this time it is unknown whether immune suppressive treatment (ex. steroids, methotrexate, biologicals) increase the risk of severe COVID-19 infection."
I may stay out of public life for a week or two to see which way this pandemic develops.