Best time to take Prednisolone to lessen Nausea

[Blomps]

Im getting a lot of Nausea but taking Methotrexate as well as Prednisolone Omeprazole and Statins. Is there a better time to take the steroids rather than early mornings. On 15mg Prednisolone at present reducing gradually.

[Hidden]

Are you nauseous everyday? As it’s usually the Methotrexate that causes nausea.

[Blomps in reply to Hidden]

At present yes. I take Methotrexate weekly on Mondays. Forgot to mention also because of Pred back on Metformin as diabetes flared up after I had it under control with diet.

[Hidden in reply to Blomps]

It could well be the MXT

Were you nauseous before you started MXT?

I was OK for the first month then suddenly one evening at dinner on a Cruise they had a Special Menu, Master Chef Style & as l was reading it the wave of nausea was overwhelming.

After that I could not bear the smell of cooking & l virtually lived on cold chicken for a month, then as suddenly as it came it disappeared!

There are options, see your GP for an Antiemetic, change the time you take the MXT eventually l settled at 1.15pm after a light lunch or you can have it by Injection so it bypasses the gastric tract. Also, are you on daily Folic Acid except MXT day? As that helps will all side effects of MXT

[Blomps in reply to Hidden]

I take the Methotrexate x6 once a werk on Mondays and a folic acid the day after

[Hidden in reply to Blomps]

Do you have access to a Rheumatology Helpline ie Rheumy Nurses as they can advise & as you take other Medications it might be worth talking to your Pharmacist to find out the optimum times to take your Meds to help alleviate the nausea.

Let us know how you get on.

Kind Regards

MrsN

[Blomps in reply to Hidden]

Thanks for the help. I will let you know how I get on.

[PMRpro Ambassador in reply to Blomps]

My guy likes the mtx dose split into 2, half in the evening and half next morning. He finds it reduces the nausea - and it was the one problem I didn't have.

[Blomps in reply to PMRpro]

Thankyou

[GOOD_GRIEF in reply to Blomps]

My friend has RA, and takes a similar dose of MTX once a week. Try taking the folic acid every day except for MTX day. That stopped the nausea for her.

[Blomps in reply to GOOD_GRIEF]

Thanks will try