I've been reading recent posts about the best time to take medication and I found it really interesting because I've been wondering whether to change my own routine. I currently take 35mg Pred - originally on 15mg then upped to 40mg as a precaution against possible GCA and now hoping to reduce to 30mg next week. I take the full dose at 4.30am because I understand it gives the steroid a chance to get into the blood stream early on. My tablets are the enteric coated ones as they help with my hiatus hernia. Unfortunately, I find that when I get up about 8am, I also get the full force of the side effects - tinnitus and balance problems - which then continue to a lesser degree for the rest of the day. So, I'm wondering whether to take them after my evening meal about 7pm, in the hopes that the worst of the side effects will be during the night. Of course, I then have to juggle the dose to change to a totally different time. I was wondering whether to take say 15mg on waking and then 20mg in the evening, then 10mg in the morning with 25mg in the evening - and so on until I get to the full dose in the evening. I really do find the side effects a big problem and providing I pace myself, I'm not feeling too bad otherwise. I'd really appreciate any advice or comments.