I was diagnosed with PMR 12 weeks ago and have been quite active since my symptoms and side effects resolved 6 weeks later. Although I have no problem with yard work, gardening, or walking, when I stand for long periods I notice weakness in my legs and subsequent aching thigh muscles that continues for about two days. I first noticed it after standing at the rail of a boat while fishing Atlantic coastal waters. When my legs weakened I attributed the fatigue to working my muscles to compensate for the pitching motion of the deck. Next I got involved in engine work that required me to stand for about 3 hours. Once again, my legs weakened to the point of being wobbly and the aching muscles began the following day. This problem has since occurred 2 times more and it is now obvious that standing is a significant problem for me. Does any one have an explanation for this odd phenomenon?