Seronegative arthritis

I was diagnosed with pmr in 2014.  Have had no luck in ever getting below 10mg pred.  Tried azothiaprine but that didn't work.  Saw rheumy today.  Now to begin methetrexate!  But notice she has put on all my forms 'seronegative arthritis'. Does this mean she now thinks I have LORA - as well as or instead of pmr.  Didn't notice it until I got home so didn't get a chance to ask her.  Advice please

4 Replies

  • Only she can say - but technically one or the other I imagine since it is fairly well accepted by most people that PMR is a vasculitis of some sort as opposed to an arthritis. About 1 in 6 patients who are given a dx of PMR originally later have it revised to something else, most often probably LORA. But there is no reason why you can't have both if you are being greedy...

  • Never did like putting all,my eggs in one basket!

  • Mmm, sero negative arthritis is usually Ankylosing spondylitis or one of the other spondyloarthropathys as its not associated with a particular antibody unlike Rheumatoid Arthritis which is associated with Rheumatoid factor. 

    Spondyloarthropathy can present with hip and shoulder pain, responds to Prednisolone but doesn't respond to conventional  DMARDS, have you ever had an MRI scan of your joints to check what's going on? 

  • I have never heard of anyone with immune dysfunction without "arthritis" - it's part and parcel.  At the end of the day, PMR is a label.  Autoimmune disease is like a fisherman's net.  It's vast and not limited to a single "disease".  

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