Can anyone advise if they've had problems with Lansoprazole. I've been taking it, firstly 30mg (60mg Pred) and now down to 15mg (10mg Pred) but suffer severe watery diarrhoea, stomach bloating and stomach gurgling. Diagnosed with PMR seven months ago and a month later GCA, much to my devastation. Very unhappy at having to take Pred as my mother was on it - she too had PMR - and we both felt back then - twenty years ago - that the side effects were appalling. So was really surprised that in all these years - it's been around since 1955 - nothing else has been produced from the Pharmaceutical companies that was safer to take. I'm 67 years old and was fit as a fleawith a cast iron stomach before all this come on. Do worry how much damage all the medication (also on weekly dose Alendronic Acid) is doing longer term. I read somewhere that pro-biotic yoghurt is effective as an alternative stomach buffer, does anyone have any experience of using this as an alternative stomach protector?