I was diagnosed PMR with raised ESR to 40 two years ago. Everything stabilised with lots of drugs. I was always at about 28-34 ESR. Now all of a sudden ESR raised again to 55 is this serious? I don't know what all this means and my Doctor is being very cagey. HELP! I am 44 years old now. I cannot allow myself to put on weight as I have lax joints and arthritis this also worries me. Constant dislocations will get worse if I put on weight. Dislocated left ankle last year just getting up out of the chair.