IVF with ICSI

[americanuser]

Hi,

My husband has PCD and we have recently gone through a failed round of IVF with ICSI. His sperm are not motile, and I'm concerned that it is the reason why our first pregnancy ended up with a miscarriage (blighted ovum to be precise). I'm in the States and there doesn't seem to be much PCD support or understanding, especially when it comes to infertility. Does anyone here have experience with IVF and ICSI being successful? I'm looking for hope, but keeping my feet on the ground for what I know could be a blow to our future family.

Thank you.

[FPolly]

Hi!

I’m sorry to hear about your in successful rounds of IVF. It’s a tough process.

We have just had our second round( I have PCD) I belong to a uk forum and have seen a few ladies post in there re: their husbands who have Cystic Fibrosis which clinics seem to have quite a lot of experience with.

They may be able to help support your answer also with their experience also.

I wishing you every bit of luck going forward in your next round!x

[Karlo]

Hello. I have PCD (zero motility as well) and my wife and I went through what you are currently going through right now. Our second round of ICSI was successful and my happy and perfectly healthy baby boy is three months old now. It's a grueling process and anyone that hasn't been through it will never understand just how mentally and physically exhausting it actually is. The only advice I can offer is to find good fertility doctors that understand the problem they're dealing with. Also, try to get as much mental rest as possible while staying physically active as much as possible. The same goes for your husband. At last, don't give up hope. Good luck.

[cctemplet in reply to Karlo]

Did you and your wife do the PGS testing of your embryos or did you guys do a fresh transfer? (Transfer on day 5)

My husband is 41 and has Kartagener Syndrome/PCD. He has zero motility, no children. We went through our first round of IVF with ICSI in December 2018. We had one embryo that was PGS tested. It came back as mosaic (abnormal & normal chromosomes) and was a female. We transferred and it didn’t implant. We start our second round of IVF next month without testing (doing a fresh transfer) but we are using 50% donor sperm and 50% my husbands sperm that was recommended by the fertility specialist whom isn’t very knowledgeable of his condition. Praying it works this time! It is so good to hear a successful story!

[Karlo in reply to cctemplet]

Hi. We didn't do any pgs testing. In our first cycle we had 7 embrios, 3 of which made it to day 5 (2 blastocysts and one in hatching phase). The first transfer didn't work but the second transfer (the hatching was successful and we have a perfectly healthy 14month year old boy.

I consulted with a well known children genetics expert who assured me how unlikely it is that my condition would be active in my child, so we decided to do no testing of embrios.

Also my fertility doctor and especially the biologist-embriologist doing the ICSI procedure were both familiar with my condition and have had success with other patients with the same condition in the past.

Good luck on your path and be persistent. If you have more detailed questions feel free to PM me.

[Freddo_8]

Hi Americanuser,

My husband has PCD with 0% motility and I too had a blighted ovum last year, it was our first IVF attempt. I know exactly how you must be feeling.

I’m currently part through way our second attempt (egg collection was today) - praying all works out for us this time 🙏🏼

All the best

X

[americanuser in reply to Freddo_8]

Freddo_8 how amazing how similar our story is. I had egg retrieval yesterday. They were able to get 12 mature eggs. Of those 12, we have 4 embryos growing. Hope to do a transfer on Sunday, December 2.

[cctemplet in reply to Freddo_8]

Did your second attempt work?

[Freddo_8 in reply to cctemplet]

Hi cctemplet,

Yes it did, I’m due next month. I hope all goes well for you.

X

[cctemplet in reply to Freddo_8]

Awesome! Congratulations!

[Freddo_8]

Oh my goodness, how amazing! I had 17 collected but will find out how they are doing in the morning. We’re hoping for transfer on Monday 3rd..

How many did you have transferred last time? I had two.

Wishing you all the luck in the world 🤞🏼

[americanuser in reply to Freddo_8]

We transferred one last time and will transfer one again this go around. Good luck to you too!

[cctemplet]

My husband is 41 and has Kartagener Syndrome. He has zero motility, no children. We went through our first round of IVF with ICSI in December 2018. We had one embryo that was PGS tested. It came back as mosaic (abnormal & normal chromosomes) and was a female. We transferred and it didn’t implant. We start our second round of IVF next month but are using 50% donor sperm and 50% my husbands sperm. Praying it works this time! Did you end up doing IVF with ICSI?