Why worse in the mornings?: Why do we... - Pernicious Anaemi...

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Why worse in the mornings?

Chickens44 profile image
11 Replies

Why do we feel worse in the mornings? I’m not too bad when I first get out of bed (never early, usually about 9.30 am), but after getting dressed, having coffee, and do a couple of small things, and I mean small, like putting the washing in the machine, and taking dogs for a 10 minute walk, I’m knackered and just feel off, fatigue comes on, burning pain. I know I’m at that ‘difficult’ time, 4 months into SI EOD, but sometimes by the afternoon/evening I feel a bit more with it. I usually sleep quite well, although I did have trouble dropping off last night.

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Chickens44 profile image
Chickens44
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11 Replies
JesusMercy60 profile image
JesusMercy60

good morning Chickens44,

I had the same thing this morning, I'm at my 4th month as well, I was totally off this morning mostly mentally and yes my nerves in my feet and just off. some mornings are better after my injections, last week I started everyday injections so I would not have the day of no injections a total slump with more symptoms. I was on eod injections for 3 months. my afternoons I had nothing left in me. so now i tried .7 ml in the morning and the last of .3 ml in the eve. but I know at night my feet are tingling sooo much and yesterday was the first day of itching and tingles so I know that they are healing. the extra dose of every day increased my symptoms but at the same time they are healing faster. but today was hard to cope but I just did my injection and I feel better. I should take it easy still though, I think your body is just going through the healing still. 4 months is early still.

Chickens44 profile image
Chickens44 in reply toJesusMercy60

Yes, I keep reminding myself I am still a ‘work in progress’ and I’m not finished yet. Like other people, my symptoms seems to change from day to day. Fatigue one day, then brain fog, then burning pain. And recently I’ve got terribly itching again, my hands, my back, my head. And spots. So annoying, but I keep praying that one day all this will be a distant memory.

JesusMercy60 profile image
JesusMercy60 in reply toChickens44

oh yes Chickens44,

I read the posts over and over during the day's and our symptoms are mostly all the same and on different day's and time frames, but it's all the healing going on, I welcomed the itching yesterday as I know it's one of the healing symptoms I read but the burning I loose my strength and start to worry again that something is not working. this morning at Church Mass I was praying as I felt I was getting close to being back at the dementia stage my mind was so off but after my shot I feel so much better again, so it's the B12 our bodies and brain are starving for. I pray so much during the day then He shows me the post's of everyone to learn. I'm so glad I read your post today. the nerves getting worse at times also scares me of "oh know" is the b12 not working? I just need my shot and the body is healing.

Chickens44 profile image
Chickens44 in reply toJesusMercy60

Just the same, sometimes I wonder if it will ever get better. But as they say, lack of patience is one of the worst symptoms of B12 deficiency, and I just want to feel well now. But it’s great having the support of all the people on here. x

Hockey_player profile image
Hockey_player in reply toChickens44

I think it will get better! I am very lucky that my case was diagnosed very early. I have managed to get back to complete normal.

Chickens44 profile image
Chickens44 in reply toHockey_player

Unfortunately it appears I may have been suffering for 20 years. Was told fibromyalgia in 2004, although I have had more anxiety and fatigue over the last 6 years. So still a way to go ….

Hockey_player profile image
Hockey_player in reply toChickens44

I hope you make a complete recovery soon! Hang in there!

WiscGuy profile image
WiscGuy

Have you ever had B9 (folate) and B6 tested? If either of those are deficient, that could could be contributing to your symptoms.

Chickens44 profile image
Chickens44 in reply toWiscGuy

I have and am taking folic and a B Complex

B12again profile image
B12again

It’s common for individuals undergoing B12 treatment to experience ups and downs, especially during the early stages. You mentioned you’re four months into self-injection every other day (SI EOD), and this can indeed be a “difficult” time for some. The body takes time to adjust, and it’s possible that some symptoms may seem to worsen or fluctuate as healing occurs. This is part of the process often referred to as “reversing out,” where previously damaged areas begin to recover. As these areas heal, the body may temporarily re-experience symptoms, sometimes even in different or seemingly random ways. This can explain why fatigue and pain seem worse at certain times, especially in the mornings when your energy reserves are low after sleep.

This kind of symptom fluctuation can feel discouraging, but it’s actually a sign that your body is beginning to heal. Your nervous system, muscles, and other tissues may still be catching up with the vitamin replenishment, and as healing takes place, the body can respond in unpredictable ways. Over time, as B12 floods your system, these symptoms should reduce.

Blood cells, particularly red blood cells, have a turnover rate of about 120 days. This means that your body is constantly producing new red blood cells to replace the old ones. In the context of B12 deficiency, this process is significant because B12 plays a crucial role in red blood cell production.

When B12 levels have been low for an extended period, the body’s ability to produce healthy red blood cells is impaired, leading to fatigue, weakness, and other symptoms. Once you start B12 injections, it can take time for your body to begin producing sufficient healthy red blood cells again. Given the 120-day turnover, it’s important to realise again, that you’re still in the relatively early stages of recovery, especially since you’ve only been on B12 injections for about four months.

The fatigue and symptoms you’re experiencing in the mornings could be due in part to the fact that your red blood cell production is still in a transitional phase. As your body continues to adjust to the B12 injections, it is gradually producing healthier cells, but this process takes time. The early morning fatigue and pain may be linked to the body’s energy reserves being lower after sleep, as well as the ongoing recovery of your blood cells and tissues.

Over time, as more healthy red blood cells are produced and your body becomes better at delivering oxygen and nutrients to your muscles and tissues, you should notice an improvement in energy levels and a reduction in symptoms like morning fatigue and burning pain. Until then, it’s important to be patient and give your body time to heal fully from the effects of long-term B12 deficiency.

With regard to magnesium, it’s worth considering adding this into your routine. Magnesium works in synergy with B12, supporting nerve health and reducing muscle aches and fatigue. Many people find that incorporating magnesium, such as the powder form I get from Vitamin Express (called Magnesium Synergy), can help reduce the burning pain and fatigue associated with B12 deficiency, for me it stopped morning headaches. It can also support better energy levels throughout the day, possibly alleviating some of the symptoms that are worse in the mornings.

As always, the journey with B12 recovery can be gradual, and pacing yourself, especially in the mornings, is important. Consider spreading out activities to conserve energy and allow your body time to adjust as it heals. You’re on the right track, but do be patient with yourself as your body continues this process.

Chickens44 profile image
Chickens44 in reply toB12again

Thanks, a good reply which I shall keep and read again. I have to say that each day I have some symptom or other, I tell myself it is my body going through changes. , which, I hope, means I am on the right track, although I don’t always feel happy about it, but I don’t worry as much as I did. Looking back I’ve had a rough few years with family illness, loss, and just generally not in the best place. So only way is up!

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