Someone posted that some of us inject 2 to 3 times a day. I was going to comment some of us inject 4 times a day but never found that comment again.
I personally did trials of 1.2,3,4 times a day. Other than the 4 times a day it was about getting more B12. Then it came to me that more frequent might be more effective. And if it was then current incorrect conclusions about amounts and frequency would prevent that from being considered. That lead to my understanding that 4 hours after an injection the effect is starting to wear off.
What works for me does not work for me as all trials work for me. Some have been shown to have superior results.
Still working on it using a rational approach. To find out what works best for me given my differences.
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WIZARD6787
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I went over my notes of my consultation with a B12 consultant. He said all but 2% of an injection is peed out after 6 hours so to review after 4 hours could likely maintain levels for longer.
I wish I had the funding to do experiments or someone else did them. All I can do is trials.
Most of the 'studies' I have read are simply white paper studies which are nothing more than a review of current understanding/data and the author's views on them. Often repeating unsubstantiated assumptions.
The over-riding goal still seems to be a so far futile search for definitive biomarkers in the hopes that that will lead to better treatment.
Other than the EOD protocol and the MMA Homocysteine testing there have been no meaningful advances in the last 1/2 century. The new testing only meaningful in that a clinician unable to make a correct diagnosis by symptoms might be able to with the MMA Homocysteine testing.
The concept of optimising co-factors is really a seems like it is a good idea thing and still based on the current ranges.
My hypothesis on frequency born of imagination has some value to me so far. Other than that so far I have not found anything new other than the rationale for current understanding is flawed. Never worked on a subject that was not the case.
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