So we ordered some panpharma b12 injections which arrived yesterday. My partner has a b12 level of 123 with neurological symtoms and gp refuses to treat. I just got my results from my b12 test result last week a level of 202 which gp said was normal. Maybe this was abit stupid but as I have symptoms I'd do a loading dose, he was planning on doing injections every other day until no further improvement. I went first as my partner was very anxious, about 20 seconds after injection I fainted, this has happened to me previously with some vaccines. My partner was petrified he thought I'd died and was ringing 999 when I came around wondering what on earth was going on. Other than being really tired today im okay but its back fired abit as I was trying to show my partner there is nothing to be scared of and he's abit dubious now to start. Iv explained its me and I have very low blood pressure but after that he was abit scared. He knows he's okay with it as had the loading dose from gp but he just kept freezing when trying to inject. We are thinking of getting smaller needles so he can inject into stomach fat. Anyone able to advise on this. I'm not going to do anymore as I think iv had a reaction, same thing happened after my bcg as a child. Has anyone else had a reaction after b12
B12 self injection: So we ordered some... - Pernicious Anaemi...
B12 self injection
I have PA and find that oral B12 works for me. Maybe it's worth your husband trying it as well. If you're interested message me and I'll give you all the details on how to do it.
charks.....if you have PA, (which means you don't absorb B12 from food), how can oral B12 work for you? Genuine question, am interested to know. I wish I was ok on just oral B12
It doesn't work for everyone. But the original 'cure' for PA was oral - chopped liver. I glad things have moved on and we now have synthesized B12 as I don't like liver. But the fact that people with PA were cured with liver means that oral does work. But because people with PA don't have any parietal cells the gut has to absorb the B12 via passive absorption which is very inefficient - only about 1% of oral B12 supplement will make it into the blood. So you need to take lots. And there is another problem. The process is very slow so it means the gut can only efficiently absorb a small amount of B12 within a given period of time.
I originally took high dose pills but didn’t get much benefit from them. Most people with PA also have low acid in the gut which means that our food doesn’t get broken down very well so our gut has difficulties extracting nutrients.
So I use a B12 protocol that I believe replicates the body’s natural way of obtaining B12 from food. I buy 5000mcg B12 sublingual liquid drops, dilute it in water and drink it throughout the day. I take about 3 droppers full (15,000). Taking B12 this way means the gut has a constant supply of B12 which helps it extract enough B12 using passive absorption.
It works for me for which I am really grateful as I hate the idea of injections.
And do you find this works well enough to keep you symptom free?
Before treatment I was a mess. I couldn't even stand up without help. Now I regularly hike 5 miles. So yes it does work.
Wow, good for you!! Can I also ask how long you have been doing this for?I've been SI'ing for 6½ years, every 3 days now. This keeps all my symptoms at bay, allows me to work in a job where I walk at least 4 miles a day, I can go to the gym, be a wife, be a mum, and basically live my life. Before SI'ing I was a mess too. I was like a zombie, and I believe I would have ended up bedbound. I don't like the idea of injecting so frequently, but doing so means I live a fulfilling life. However, I do wish there was another way, but sadly tablets, drops, sprays, etc didn't help me.
It is over three years. I still have some very annoying symptoms - frequent urination being the worse - but I lead an active life. I make jewellery and, at my worse, I just couldn't do it - no fine hand motor control. The best thing about oral B12 is that I can 'top up' if needed i.e after a hike.
I stopped chocolate, ginger, citrus and raw onions and frequent urination stopped... found it on google, and it worked for me
Thank you for trying to help me but I don't eat chocolate ( diabetes type 2 ) and onions ( celiac ). And I don't eat citrus and ginger very often. I think it is some sort of nerve damage.
What type of drops do you use? I agree that slow steady absorption seems more natural. I’ve tried dissolving sublingual tablets in water, but that had no effect at all.
I buy 5,000 mcg liquid. I buy it in bulk but you can buy a single bottle from Amazon. You need a lot. I use 3 droppers full a day. Sublingual tablets are usually only 1000mcg.
I use sublingual b12. It’s a powder. This bypasses the stomach. Sublingual means under the tongue. It’s the stomach acid that destroys oral B12. Because of a lack of the intrinsic factor. I buy the powder from Amazon.
Stomach acid doesn't destroy B12. You need stomach acid to be able to digest B12. Sublingual B12 can't work because the B12 molecule is to big to permeate the mucous membrane. You end up swallowing the B12 and only 1% ends up in your blood via passive absorption. Which is why you need so much.
I would like to know what you use orally that work please. Not mad keen on needles
I use a B12 protocol that I believe replicates the body’s natural way of obtaining B12 from food. I buy 5000mcg B12 sublingual liquid drops, dilute it in water and drink it throughout the day. I take about 3 droppers full (15,000). Taking B12 this way means the gut has a constant supply of B12 which helps it extract enough B12 using passive absorption
It works for me for which I am really grateful as I hate injections. When I was a child I had to have an injection to visit the USA. The doctor had to chase me around the surgery. I knocked his phone off his desk and damaged it. He wasn't happy.
Any B12 sublingual liquid from Amazon will do as long as it is 5000mcg.
Something like this.
One can get so worked up and nervous when self injecting for the first time . I have self-injected for 9 years , using the I.M. ( Intra-Muscular) method. This year I decided to try the sub- cut method , which is not used in the U.K. ( Is obviously used in Germany as it appears on the B12 ampoule packets that we get from German online Pharmacies , as a suggested method along side I.M. Sub-cut works just as well as I.M. I inject into the front of my thighs . But you can use the tummy fat also . Sun -cut is much less intimidating than I.M.
I first draw up the B12 using a long 1 1/2 inch needle, I change to a very short , fine needle to inject-namely a 30G x 6mm needle — 6 mm is roughly 1/4 inch . I inject at 90 degrees . The B12 will take a little longer go get into the system than when using the I.M. method , as the fat layer has a lesser blood supply than the muscles . I find this to be an advantage .
I can only find one supplier of those 30G x 6mm injection needles .That is Amazon.co.uk Antonmove Stainless steel pipe 30G x 6mm £16.99 for 100
You may be able to manage a 1ml syringe with a short fixed needle but I cannot ,,without touching the sides of the ampoule . ( OUCH!)
I suggest this sub-cut method . I’m very pleased with it !
Best wishes !
And based on wedgewood advice I'm doing it this way too. Those 6mm needles are nice and short. It doesn't hurt.
Hello, like fancypants I followed wedgewood's recommendation and now use 6mm needles. They suit me much better.
Me too
Do you use hydroxocobalamin & if so what brand?
I usually use Panpharma B12 depot Ref no.16199653 1mgx 1ml ampoules
But when Panpharma was in very short supply , I used Pascoe B12 depot Ref no 07568672 ( pack of 10) 1.5 x 1mm ampoules .
Ref 07568695 Packs of 10 x 10
Pascoe works as well for me as Panpharma.
Thank you. I have only ever used Hevert and now Pascoe, which I suspect have suffered from heat and expire soon too.
I use 30G 1/2" needle yellow. 27-30G suitable
If you have pernicious anemia Administering vitamin B12 injections into your belly fat or hips― hoping that it will help melt fat in those areas―is totally ineffective.
I inject EOD usually IM but when my arms get sore I change to Sun cut I do notice a return of some symptoms but just alternate back This seams to work.
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