Goggled how B12 deficiency is treated in India.

[WIZARD6787]

I found it interesting.

Methylcobalamin is what seems to be used in that country and it is where my trials seem to be leading me.

I found it interesting that those that treat B12 deficiency believe that it can be reversed in most cases within a year.

Another piece in the mosaic that I am creating.

I wish someone else had a pattern to follow but they do not although many make such a claim. Typically ending with the damage is permanent which I have disproved or it takes years and years which I can only disprove by spending years and years and then finding a way to heal.

[wedgewood]

I’m afraid that in India , only the well-off will get treatment . There is a lot of B12 deficiency there . and many people cannot afford medical treatment .

[Nackapan]

In India it is rife.Some is due to diet and poverty.

Treatment is difficult to get to those in need.

[Bellabab]

Dietary B12 can be reversed - PA cannot be reversed. Martyn Hooper injects 5mg/ml of methylcobalamin every 2 or 3 days. I am trying to find where I can buy some and try it. His two Books are excellent

[WIZARD6787 in reply to Bellabab]

The symptoms of PA/Intrinsic factor can be reversed.

I am stunned that Martin Hooper injects that amount of Methylcobalamin and this is the first I have heard of it. The one mg every other day seems to be the measure and anything else is labeled massive amounts.

Ironically my 2.5 years of trials has lead me to currently injecting methylcobalamin 1.5 mg three times a day.

Is Hooper's current regiment covered in one of his books? I have been assuming that his books were a personal account and not going beyond the current UK guidelines which I found to be not as effective as more B12 five months ago.

[Technoid]

"I found it interesting that those that treat B12 deficiency believe that it can be reversed in most cases within a year. "

Well that depends on the cause of the deficiency and the severity of damage. If the cause is PA, injections or high dose oral will be necessary for life, so no, that cannot be "reversed in a year". In other cases, like an infection, absorption issue, diet, medication, parasites, nitrous oxide etc, injections may or may not be needed depending on severity of the deficiency and it will likely be possible to drop to oral supplementation in time, after the bulk of damage is healed and absorption recovers or the diet is correctly supplemented.

Strictly speaking, a b12 deficiency is corrected (in serum) within minutes/hours following a B12 injection. But correction of body stores of B12 and red blood cell replacement may take several months. Tissue and other damage if severe would also likely take some months. Neurological damage recovery may take years or never be fully recoverable. Issues with bone health (due to secondary Taurine deficiency) may likewise take quite some time to improve, not certain the exact timeframe but could also be years.

Whether neurological damage is fully reversible or not depends on the severity and extent of the damage and whether axons were destroyed. It doesn't matter whether the cause of the deficiency was dietary, PA or whatever it might be, if axons have been destroyed then (according to current neuroscience), it is not possible for them to regenerate.

Treatments that make this possible may appear in the future. But only a skilled neurologist would be able to tell whether axons were destroyed. Without knowing that it would not be possible to say for sure whether neurological damage is or is not fully recoverable.

If you fully recovered after years of treatment it would not disprove that in some cases neurological damage from a B12 deficiency is permanent, unless we knew for sure that axonal death was involved in your case. If there was not true axonal death of neurons, then recovery, although terribly slow, is always theoretically possible.

Wish you luck with the methylcobalamin.

[WIZARD6787 in reply to Technoid]

I understand that. It is also true that the degree of recovery and speed of recovery for a specific treatment can be measured. More B12 and a different form or combination of forms is a new treatment.

I did a 120 day trial of 2 mg of methylcobalamin every day 1.5 years ago +- and it was effective. Not as effective as 1 mg hydroxocobalamin three times a day.

I sometimes get sloppy and do not note that I am just expressing my experience and do not note that I in no way am advocating for treatment that is not done in the context of a licenced professionals advice as I am not one.

[WIZARD6787 in reply to Technoid]

Although I know I am badgering you. I ask again does either of Hoopers Books address Methylcobalamin at large doses?

I want to spend my efforts on other tasks if it does not.