Myelination and peripheral neuropathy

Worth investigating Vitamin C for potential Myelination and perpheral neuropathy.

Many websites recommend vitamin C

[jade_s]

Interesting! I will have to add researching that to my to-do list LOL. Thanks.

[Hidden in reply to jade_s]

After looking at the video of nerves I came across a website onlinelibrary.wiley.com

"Vitamin C regulates SCHWANN cell myelination by promoting DNA demethylation of pro-myelinating Genes.

I will have to go back and see where the schwann cells were !!

[Technoid in reply to Hidden]

yep. mentioned in my treatment plan.

shameless plug : healthunlocked.com/pasoc/po...

I take 100% RDA Vitamin C in my multi and my diet has nothing but vitamin C 🤗. You can take too much vitamin C (in supplement form) (contrary to popular belief), more than 2g risks kidney stone formation. A 500mg supplement (or even 1 gram for a short time) shouldnt do any harm but I prefer not to supplement anti-oxidants as, again, contrary to once popular belief, you can have too much - body needs a balance of oxidants and anti-oxidants.

But its VERY important to have enough Vitamin C and even a little extra to ensure remyelination is not held up!

[ACritical in reply to Technoid]

vitamin C, lemon/ orange/ tangerine , ascorbic acid are my triggers for developing a migraine , so I avoid them and get my vitamin C from hopefully other vegetables and fruits in my diet. I have never tested for a vitamin C deficiency though.

[Technoid in reply to ACritical]

Red Bell Peppers, Broccoli, Tomatoes and Kale are also good sources. I think full-blown Vitamin C deficiency is more or less unknown in developed countries unless one was somehow deliberately avoiding all vitamin-C rich foods. It is rarely even tested for. It's so important to remyelination though its worth making sure making sure you're getting plenty. Along with other critical stuff that builds nerve cells like collagen components, DHA, Choline and the B vitamins that grease those wheels.

[jade_s in reply to Hidden]

Oh very nice thank you! Schwann cells are mentioned in the video from Technoid, I guess they make the myelin sheath. So if i understand correctly, Vit C will help "turn on" the genes responsible for driving the myelination process of schwann cells.

[Polaris]

I’d been taking vitamin C for a long time and then read on the thyroid forum that it can affect B12 absorption !

Apparently, it should be taken two hours apart.

PS It took medics seventy years after it was discovered, to begin treating sailors, dying from scurvy on long voyages, with oranges and lemons, etc. 😰

[Hidden in reply to Polaris]

yes it can wipe out alot. I eat a lot of fruit and veg, but a lot of the younger generation don't. Burger s chips, take aways etc. Everything in moderation. PPI block acid that's needed to breakdown food.

[Technoid in reply to Polaris]

yes! But I think only Vitamin C in large supplemental dosages could cause an issue. If you're taking oral B12 I would take it with Calcium 2 hours after a meal or 1 hour before, this gives the best possible absorption without interference. Injected B12 it shouldn't affect. Good point though Polaris I should have mentioned that. I do take extra b12 with meals though anyway because why not

[Hamayeshguy]

schwann cells are in the brain and oligodendrocytes are in the rest of our body.

[Technoid in reply to Hamayeshguy]

Not quite. Hacked together this info from Wikipedia and the source linked below : Schwann cells insulate the axons of the nerve cells in the Peripheral Nervous System whereas oligodendrocytes insulate the nerve cells in the Central Nervous System. Both are types of glial cells that insulate nerves. Both schwann cells and oligodendrocytes are capable of forming myelin sheaths around axons. Schwann cells are distributed throughout the peripheral nervous system. In myelinated axons, Schwann cells form the myelin sheath around the axon. Nonmyelinating Schwann cells are involved in maintenance of axons and are crucial for neuronal survival. Some group around smaller axons and form Remak bundles.

Oligodendrocytes wrap around axons in the central nervous system.

Good resource showing the similarities and differences: pediaa.com/difference-betwe...

[Technoid in reply to Technoid]

and perhaps surprisingly, there is even a supplement designed to support glial cell restoraton and repair: prodrome.com/product/glia-oil/ . Pretty expensive though and no idea whether any research backs it up.

[Technoid in reply to Technoid]

m.youtube.com/watch?v=Es0oX...(Not working as expected?)

[Yahaci in reply to Technoid]

Have you got any medical or biology background?

[Technoid in reply to Yahaci]

I do not. I just like researching this stuff!

[Yahaci in reply to Technoid]

Research background?

[Technoid in reply to Yahaci]

Yes

[Yahaci in reply to Technoid]

Perhaps you can offer clinics in Harley Street once you're done with the research