Help symptoms worsen after 5mg folate acid daily

[Issa101]

Help

I'm on montly injections since 6 months

Neurological symptoms improved but still exit

However, GP predescribed 5 mg of folate acid daily

Since I started taking it my symptoms such as anxiety worsen a lot

Any suggestions?

[wedgewood]

Unless you are grossly low in Folate , 5 mg daily sounds very high . I would substitute it with a modest , but effective 400mcg folic acid tablet daily . This is a normal but adequate maintenance dose .

[Issa101 in reply to wedgewood]

Thanks 😊

[charlee23]

I would say that the form of folate might be not right for you. What were the levels of folate after 6 months injections?

Folic acid is synthetic form and usually badly absorbed. Would use the folate and normally 800mcg is enough maintenance dose.

[Issa101 in reply to charlee23]

Thanks

[fbirder in reply to charlee23]

Actually folic acid is better absorbed than folate in foods and is as easily absorbed as methylfolate in pills. pubmed.ncbi.nlm.nih.gov/206...

The methylfolate in pills is just as synthetic as is folic acid (indeed methylfolate is made from folic acid patents.google.com/patent/U...

[Issa101 in reply to fbirder]

So what I can do my anxiety is severe and my heart pounding most of time and my hand sweety and shaking

Shall I continue with 5 mg or stopped or decrease the dose

[fbirder in reply to Issa101]

I would stop, get some 400 mcg folic acid tablets from the supermarket, and try them.

[Martin_12]

If your B12 deficiency is inadequately treated, high folate can precipitate or aggravate the neurological and haematological consequences of vitamin B12 deficiency by increasing the demand for vitamin B12.

pubmed.ncbi.nlm.nih.gov/268...

[Issa101 in reply to Martin_12]

Maybe this the reason my neurological symptoms got worsen

So shall I stopp the folic acid or decrease the dose to 400 mcg

[Martin_12 in reply to Issa101]

You need to know the reason your GP prescribed 5 mg folic acid. What was your folate before you started the folic acid? How long have you been taking 5 mg?

[Issa101 in reply to Martin_12]

I haven't had folate level measuref but my GP told my that folic acid and b12 working together and predescribed 5mg folic acid for me

[Martin_12 in reply to Issa101]

If your folate wasn't measured at all you should stop the 5 mg folic acid right away. I would ask the GP to do a folate measurement ASAP, then get folate measured after about a month and use that result to decide whether or not to take folic acid, and how much to take.

[Curlygal in reply to Issa101]

That's shocking. Your GP should definitely not have prescribed without measuring folate first!

[Issa101]

Two weeks since i have started taking 5mg folic acid

[Curlygal in reply to Issa101]

I would perhaps suggest actually stopping for a week or two to let the folate levels drop, and then take 400mcg daily.

[Issa101 in reply to Curlygal]

Thanks 😊