anti parietal cell antibody test For b12

[Ulrich-vi]

anti parietal cell antibody test For b12 is it worth ?

[Albertina_G]

A parietal cell antibody test is not a frequent test and it is only done when a person has signs and symptoms that suggest vitamin B12 deficiency. So if you are seeing some symptoms of vitamin B12 deficiency then it is worth doing.

[robinsnestwalke]

Yes, if you want to find out if you have Pernicious Anemia, and add a Gastrin Serum Test to the the order as well, that will solidify it.

[Nackapan]

I had this test right at the start. A positive test can mean all sorts and is not used in isolation to diagnose PA

I had a negative result which still does not rule our PA but a lower % of possibility.

I certainly cannot absorb b12 from food or tablets. Or else my body not bothering to even try now . on injections for life .

The intrinsic factor antybody test is used . It picks up about 50 % of those with PA.

Should really be done before In jections start as high levels of b12 in your blood csn causes a false positive ???

Minefield.

I dont know the science behind it all

But neither do the medics !!

[fbirder]

On its own - no. About 10% of people without PA test positive for GPC antibodies.

But it can be supporting evidence for PA.

My diagnosis was based on - undetectable levels of B12, symptoms of a B12 deficiency, gastric atrophy in the fundus and corpus but absent from the antrum, metaplasia, high gastrin and positive for GPC antibodies.