Could my body not like synthetic form... - Pernicious Anaemi...

Pernicious Anaemia Society

31,973 members23,121 posts

Could my body not like synthetic forms advice please

sbadd profile image
14 Replies

So ive posted alot regarding my horendous side effects from b12 injections last one 10 weeks ago and most symptons have resolved apart from tachy in last few weeks, however yesterday took a magnesium tablet as still have muscle twitching, within around hour half later felt extremely heavy in arms and legs and became tachy, heart ok this morning but woke with numbness in toe and legs arms still quite heavy, prior to this legs arms were considebly lighter in recent weeks however were like this just after injections, has anyone else experienced this im wondering if my body just doesn't like synthetic forms of vitamins, any advice much appreciated

Written by
sbadd profile image
sbadd
To view profiles and participate in discussions please or .
Read more about...
14 Replies
Bigdog1989 profile image
Bigdog1989

This is how I feel! I have svt of the heart and it’s well controlled but lately it feels it likes beating out of my chest, however I believe it’s because I’m due my injection again as my last one was about 10 weeks ago also, things had improved when I got them, and got real bad a couple of weeks back

sbadd profile image
sbadd in reply to Bigdog1989

Im scared to have any more injections because of the side effects, my store levels were low due to diet not PA my levels around 1000 or just over as tested week and bit ago (b12)

How long with diet related b12 should you require injections?

Gambit62 profile image
Gambit62Administrator in reply to sbadd

in theory, if you don't have an absorption problem then you don't need injections as you should be able to maintain your B12 levels by supplementing B12 - doses of around 10mcg a day should be sufficient.

I say 'in theory' as injections can have an impact on where people need to maintain serum B12 levels and make it much higher for some people. However, that doesn't apply to everyone.

Suggest you try using oral supplements and see how you go.

Did you have macrocytosis when you were diagnosed? If so it may be that your potassium levels need monitoring. It is very easy to overdose on potassium and the symptoms of overdose are as unpleasant and potentially life-threatening as low potassium so please consult a medical professional.

sbadd profile image
sbadd in reply to Gambit62

Not sure about the macrocytitis but potassium checked week ago reading 4.0

Range was from 3.5 upwards

Gambit62 profile image
Gambit62Administrator in reply to sbadd

if it is in range then that is okay

sbadd profile image
sbadd in reply to Gambit62

Thanks i think ill hold off on any further injections atm

GastritisB12 profile image
GastritisB12

I had a fast heart rate sitting and standing/walking fro. B12/Folate deficiency. In my case I needed more injections not less. When were your loading doses and how many did you have?

In my case my fast heart rate resolved a bit after 6 loading doses but 3 weeks later it came back! Even though my B12 must have been high. So I had another 10 alternate day injections after which it resolved and didn't come back for 5 weeks after which I had another B12.

sbadd profile image
sbadd in reply to GastritisB12

I had 6 loading doses last one ten weeks ago but didn't get tachy until 4 weeks ago which passed but has now come back i never had any of this prior to injections?

sbadd profile image
sbadd in reply to sbadd

Also if not an absorption problem then when are reading likely to be accurate how long do you wait, and how many injections do you require if stuff keeps coming back, ive only just recovered from side effects apart from these recent ones so do not want to experience living hell again, i have 3 children 9,11 and 14 and could not even function properly after injections, luckily they were on school holidays at the time, not sure what to do

sbadd profile image
sbadd in reply to sbadd

My active b12 read normal but my stores were low

GastritisB12 profile image
GastritisB12 in reply to sbadd

Ok that's different to me. My fast heart rate was when my B12 was low before treatment. I have no clue about your symptoms so I'll shut up now :)

fbirder profile image
fbirder

There is absolutely zero difference between 'natural' B12 and 'synthetic' B12. Indeed, the 'synthetic' stuff is made in exactly the same way as the 'natural' stuff - it is produced by bacteria in fermentation vessels. In one case that vessel is an animal gut, in the other a stainless steel tank.

There is no possible test that anybody could use to tell the difference between B12 produced in a gut from that produced in a tank.

sbadd profile image
sbadd in reply to fbirder

Ok thankyou

sbadd profile image
sbadd in reply to sbadd

Obviously my body has been low so may take some time, thankyou to all with advice

You may also like...

Advice please on different forms b12

finished my last loading dose 4 weeks ago was on the cyno shots, still quite tired and have...

Confused & could do with some advice please...

shouldn't stop being given the injections. The results on 15/03/2023 were.. Serum ferritin...

Need advice please. Could this be the answer after 10 years!?

Next steps on my GP journey - advice please!

tablet or injection since 5th Feb.) 3. I want to ask for a therapeutic trial of B12 injections -...

Advice regarding my mums bloods please

morphine. However still gets terrible pains. Her feet are almost always freezing and has burning...