Central nervous system

[toph]

Can B12 deficiency cause demyelination of the central nervous system or is it isolated to your peripheral nerves?

[pvanderaa]

Subacute combined degeneration is damage to the spinal cord.

Symptoms like Short term memory loss up to schizophrenia are all from damage in the brain.

[Nackapan]

In my case it wasn't isolated to peripheral nerves. It tends to affect the central nervous system if you are older 45 + also if low levels and late diagnosis and treatment. That's what I was told. Usually a I referral to a neurologist is done so they can assess. I'm not medical but was told this by medics. Also that if the demyelination has occurred it can heal with treatment but at a very slow rate and continues to heal for 3-6 month or more perhaps.

Hope helpful

[Gambit62 Administrator]

B12 is used by at least two processes that maintain healthy nerve function - maintaining the insulating myelin layer around nerve cells - but it also plays a part in the processes that reset neuro-transmitters.

[Sleepybunny]

Hi,

Neurological Consequences of B12 Deficiency

PAS news item

pernicious-anaemia-society....

PAS article about SACD, sub acute combined degeneration of the spinal cord, access to PAS members only.

pernicious-anaemia-society....

Blog post from Martyn Hooper's blog, mentions SACD

martynhooper.com/2010/09/21...

I am not medically trained.