Hello. Today is June 16th. My B 12 level is 119.3. I got my first B 12 shot June 1st. I started B 12 supplememts (one per day, 1000 mcg) on June 11th and got a second B 12 shot June 13. I had energy for up to three days after the shot, them then my energy levels crashed and all my symptoms of severe depression and no energy have returned. But my depression has worsened since I have received the shots. I don't have a plan to commit suicide per se, but I'm overwhelmed, withdrawing from people I love and sometimes wish I was never born because of all the numerous health problems I have to deal with (I'm on 18 diffrent kinds of medication daily). Long story short, do B 12 shots and supplements worsen pre-existing mental health conditions? Or is it simply a matter of low B 12 aggravating my mental health problems to begin with? My doctor is only giving me supplement untill my next doctors visit. I do have bipolar disorder and on medication but my depression is a lot worse now. I also don't drink, use drugs. Any advice what is happening and why?