Hi all, I posted before (https://healthunlocked.com/pasoc/posts/136700379/stunned-in-a-good-way) when I managed to persuade my GP to begin me on B12 injections. Because my serum B12 test had been within range (176 pmol/l (110-664)) and I had unfortunately made testing of MMA and homocysteine pointless by taking some sublinguals in my despair, she, in discussion with consultants in haematology and neurology agreed to a therapeutic trial instead. I'm to see the neurology consultant on the 7th December because he saw me when I was much more ill in summer, so will theoretically have some kind of baseline from which to judge any improvement. They think (and I can totally see their point) that because my diagnosis is relapsing/remitting MS, and because I have very gradually been improving since my worst point in February anyway, that it would be difficult to know whether any improvement in symptoms would have happened anyway.
Also, as well as very very slowly improving, my symptoms do tend to come and go a bit. Mostly I still have tiredness, intermittent numbness/tingling, some pain in my pinkie finger and foot and tired eyes, sometimes a kind of cold skin sensation too. My GP said something like 'if you have a miraculous improvement we'll know we're on the right track', but I know that neurological symptoms can get worse before they get better and can be quite slow to improve, so my question is, how can I know, for the purpose of a therapeutic trial, whether the B12 is helping?!
I'm getting an injection every other day and have only had 3 so far. My colour has definitely improved and I feel a lot less cold on the day of the injection. I feel quite sleepy soon after the injection too! Any advice appreciated