Pernicious Anaemia Society
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Anemia Profile: Megaloblastic

Anemia Profile: Megaloblastic

Anything unusual here?

See link (https://healthunlocked.com/pasoc/posts/135301103/very-confused) for background, but as a quick summary, my B12 serum is now good after taking sublingual supplements for the last several months (>2000). Yet I am still having low B12 symptoms, particularly feeling cold, shortness of breath, and neurological. Also, lowish RBC, highish MCV still.

Judging from these tests results, should I just give up on thinking that my problems are B12 related? I originally tested in the low 200's prior to beginning treatment.

3 Replies
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Hi,

If you were supplementing with B12 prior to having MMA and Homocysteine tests, it's possible that the results of those tests may have been affected by the supplementation.

b12deficiency.info/b12-test...

stichtingb12tekort.nl/weten...

stichtingb12tekort.nl/weten...

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symptoms of B12 deficiency overlap with a number of other conditions.

If all the evidence you have is pointing away from B12 deficiency - would suggest that you look into other possibilities and rule those out.

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