Do parietal antibodies come and go? - Pernicious Anaemi...

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Do parietal antibodies come and go?

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I know the intrinsic factor test only comes back positive half the time in AIG, is it the experience of members that the parietal antibody test result can come and go too? I tested myself some years ago and was negative, I didn't test intrinsic factor ... does that result rule AIG out for me?

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Galixie profile image
Galixie

My personal experience is that the parietal cell antibody test is just as flawed as the intrinsic factor antibody test. I initially tested positive for parietal cell antibodies in 2008 (intrinsic factor antibodies were not tested at the time). A year later I tested negative for both parietal cell and intrinsic factor antibodies and have been in diagnosis limbo ever since.

What does AIG stand for? (I am assuming you're not referring to a bank I've seen commercials for, lol.)

in reply to Galixie

Autoimmune Gastritis. There seem to be a lot of synonyms for this.

Thanks, that's really useful.

Hillwoman profile image
Hillwoman

Yes, they can. I haven't tested GPC abs in recent years, but once upon a time they varied from absent all the way through to 'strongly positive' and back again, finally settling on the latter.

Edit: oops, bad phrasing - the GPCs settled on strongly positive!

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