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ljmulledy profile image
22 Replies

I just started self injecting weekly. I hypermetabolize b12, i lift weights, and can tell whtn my b12 is low. Its like pulling the energy plug....60 to zero in minutes. . i use to go to drs but it was inconvenient. Self injecting in the deltoid is easy

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ljmulledy
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22 Replies
Gudgy66 profile image
Gudgy66

I am a Natural Competative Bodybuilder and have been diagnosed with PA some years ago. At first it was ok on a three monthly jab. But since dieting for a show last year the symptoms are much worse. Do you self inject methyl or hyroxo? As I am thinking of self injection.

ljmulledy profile image
ljmulledy in reply toGudgy66

Cyanocobalamin 1000 mcg or 1 ml weekly

drs Rx

Bluedragon profile image
Bluedragon in reply toljmulledy

Have you tried Hydroxocobalamin? Better really, though some people do well on other types. I guess you must be US?

ljmulledy profile image
ljmulledy in reply toBluedragon

I am in us. ill have to ask doc. My PA went 4 years without diagnosis. I just thought it was fatigue. I developed parkinson like tremors in my hands and heart issues. The b12 i have im grateful for, but ill inquire with my dr.

ljmulledy profile image
ljmulledy in reply toBluedragon

Yes, Boston....best health care in the country.

Catherine50 profile image
Catherine50

Where do you buy your b 12th solution from and what strength is it

ljmulledy profile image
ljmulledy in reply toCatherine50

in a few secondsljmulledy

Cyanocobalamin 1000 mcg or 1 ml weekly

drs Rx

Reply

Methylcobalamin is the form of B12 you should be taking. Cyanocobalamin is the form you want to avoid, it’s basically cobalamin bonded with cyanide and commercially produced. This is the type of B12 that is produced by bacteria fermentation for the purpose of low cost, cheap vitamin and food fortification. This is the kind of B12 that people fortify and all the different types of food, cereals and stuff like that out there at conventional grocery stores, it’s the one that’s really bad for you.

Try this company k3nowmd.com/b12-injections

They only sell Methylcobalamin and you can literally buy a 30ml vial for 110 bucks. That includes all syringes.

taka profile image
takaAdministrator in reply toashley_thompson87

"Methylcobalamin is the form of B12 you should be taking. "

Not necessarily. Some may prefer it over other versions for their own reasons however as shown in this paper there is no advantage of methyl over hydroxo or cobalamin. ncbi.nlm.nih.gov/pubmed/258...

"Cyanocobalamin is the form you want to avoid, it’s basically cobalamin bonded with cyanide and commercially produced." "...it’s the one that’s really bad for you."

ALL the types of B12 available to us in injectable / lozenge / spray / tablet etc forms are ALL commercially made, methylcobalamin included.

Yes the cyano in cyanocabalamin indicates cyanide forms part of this. The levels of cyanide from supplementing with cyanocobalamin are minuscule and are easily eliminated by your body in the same way that the minuscule amounts of cyanide found in various common foods are eliminated.

Cyanocobalamin is not "really bad for you" - it is fact the reverse... lifesaving if you have a B12 deficiency or PA!

ashley_thompson87 profile image
ashley_thompson87 in reply totaka

Research has shown methyl to be higher quality than cynocobalomin.

Cyno is low grade, low quality and slightly toxic. Your body simply doesn't just rid itself of the cyanide molecule. It's a bit more complex than that and actually requires more work on a biochemical level.

Yes, some people will still benefit from using the cyno form but it must be converted into a usable form of b12 first. In order for that conversion to take place, the cyanide bond must be released.

I don't know about you but I don't believe cyanide no matter how "miniscule" an amount is healthy for the body.

Adding more cyanide to the amounts we are exposed to on a daily basis is probably not a great idea. Why take something that contains cyanide when there are better options available?

taka profile image
takaAdministrator in reply toashley_thompson87

Do you have any links to papers showing methyl is better than cyano? I'd be very interested to read them if you do. :-)

No medication in injectable form will be low grade and low quality so I disagree that cyano is low grade etc.

What about the body's need for adenosylcobalamin? Your body will still need to convert Methyl to adenosyl if you only take methyl.

nature.com/ejcn/journal/v69...

ljmulledy profile image
ljmulledy in reply toashley_thompson87

I am not concerned....

ljmulledy profile image
ljmulledy in reply toashley_thompson87

Provide the research please...

fbirder profile image
fbirder in reply toashley_thompson87

Research has shown methyl to be higher quality than cynocobalomin.

No it hasn't.

Cyno is low grade, low quality and slightly toxic. Your body simply doesn't just rid itself of the cyanide molecule.

Yes it does. There is less cyanide in 1 mg of cyanocobalamin than there is in a small glass of prune juice.

Please stop posting scare stories.

ljmulledy profile image
ljmulledy in reply tofbirder

Thank you....i would rather take my chances with a little cyanide than ever go back to the way I felt when I wanted to be dead....

ashley_thompson87 profile image
ashley_thompson87 in reply tofbirder

Im simply stating from the research that I've done makes me believe methyl is the superior form.

I prefer to take my b12 without cyanide.

Can you tell me why you would prefer the cyno over the methyl?

I can't see one reason. Methyl is now widely available and affordable.

This is an interesting read if your interested. health101.org/art_methylcob...

ljmulledy profile image
ljmulledy in reply toashley_thompson87

I read this article, showed my Dr. The article, he says it's not an issue. He diagnosed me, treats me.? He is the expert...

ljmulledy profile image
ljmulledy in reply toljmulledy

Some people care more about being right than being well....smh

fbirder profile image
fbirder in reply toashley_thompson87

Can you tell me why you would prefer the cyno over the methyl?

Well, being in the UK I would prefer hydroxocobalamin as that is cheaper, more stable and easier to get in injectable form that methylcobalamin.

In the US, cyanocobalamin is cheaper, more stable and easier to get in injectable form that methylcobalamin.

Methylcobalamin offers no advantages over other forms. The stuff about it not needing to be converted to one of the active forms (yes, there's more than one) is completely irrelevant.

Because, the first thing that happens to any form of B12 when it enters the cell is that the enzyme MMACHC removes the upper ligand (be it methyl, cyano or adenosyl) to form a cob(II)amin - which is then converted to the required active form (methyl or adenosyl).

I note that the article you referenced is pretty old. There's some new stuff that's superseded that -

ncbi.nlm.nih.gov/pmc/articl...

Title - Cobalamin coenzyme forms are not likely to be superior to cyano- and hydroxyl-cobalamin in prevention or treatment of cobalamin deficiency

Jeast profile image
Jeast in reply tofbirder

Thanks! Been going round over this. Got hydroxy in the hospital, but can only find cyano to si, and have been worried about this.

ljmulledy profile image
ljmulledy in reply totaka

Exactly right. I have been injecting cyanocobalamin for several years and i feel great physically and mentally

ljmulledy profile image
ljmulledy in reply toashley_thompson87

Not according to my Dr. What I am taking is appropriate. The "cyanoco" or cyanide is a non issue. Many pit fruits contain cyanide. Talked to Dr. about it and the form of B12 Im injecting is appropriate.

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