doityourself: hi everybody, I have just... - Pernicious Anaemi...

Pernicious Anaemia Society

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doityourself

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hi everybody, I have just moved to Germany and the doctor I saw here for my first jab seemed to be far more supportive of my situation. Can anyone tell me which is the best form of B12 to be injected with because it seems to be different here?

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It depends, some people prefer methylcobalamin, others hydroxocobalamin, others cyanocobalamin, perhaps ask your Dr which one he/she recommends for you?

You may find this research of interest:

Treatment of vitamin B12 deficiency-Methylcobalamine? Cyancobalamine? Hydroxocobalamin?-clearing the confusion.

ncbi.nlm.nih.gov/pubmed/251...

Abstract

Vitamin B12 (cyancobalamin, Cbl) has two active co-enzyme forms, methylcobalamin (MeCbl) and adenosylcobalamin (AdCbl). There has been a paradigm shift in the treatment of vitamin B12 deficiency such that MeCbl is being extensively used and promoted. This is despite the fact that both MeCbl and AdCbl are essential and have distinct metabolic fates and functions. MeCbl is primarily involved along with folate in hematopiesis and development of the brain during childhood. Whereas deficiency of AdCbl disturbs the carbohydrate, fat and amino-acid metabolism, and hence interferes with the formation of myelin. Thereby, it is important to treat vitamin B12 deficiency with a combination of MeCbl and AdCbl or hydroxocobalamin or Cbl. Regarding the route, it has been proved that the oral route is comparable to the intramuscular route for rectifying vitamin B12 deficiency.European Journal of Clinical Nutrition advance online publication, 13 August 2014; doi:10.1038/ejcn.2014.165.

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