Dear Friends, some of you were very helpful in filling up the repository about the effect of Mannitol on Parkinson's disease. It took us a while to release the results because we came to the conclusion that we need results that are more then 6 months of follow up. The reason is that Placebo effect is very strong on PD, and while not many pharma companies will take this under consideration, we wanted to be conservative.
Please note that the Mannitol research is based on tests conducted on mice. The test on mice lasted 4 months, which is equivalent to 4-6 human years. So patience is needed in order to verify if Mannitol has the same effect on humans.
Clinicrowd is a crowd-based platform dedicated to collect and analyze real evidence data from patients who choose to take nutraceuticals which are approved by the FDA as safe for human consumption. Unfortunately, there is no economic incentive to test these substances in official clinical trials, although they have the potential to help patients.
CliniCrowd has launched a generic, broad, on-line, protected platform which investigates and validates scientifically-based, safe, affordable and easily-accessible solutions for diseases that, to date, are not being researched due to lack of financial incentive. These solutions, can lead to a healthier and better life for individuals with various ailments and medical conditions, including, Parkinson’s disease, Alzheimer's disease and more. The Platform provides analytics and shared insights allowing the individual participant to better manage her/his personal symptoms; improving and impacting the lives of all those who suffer from the same illness. CliniCrowd is not a pharmaceutical company nor a medical consultant. We see our role as providing data and connecting the dots to provide evidence, backed by a wealth of data. By the Crowd - For the Crowd.
As first proof of concept, to leverage the experience of the Crowd, CliniCrowd launched:
Mannitol for Parkinson’s patients - Early Results are Promising
Since the launch of the platform in 2017, Parkinson’s patients from 42 countries worldwide decided to test Mannitol through CliniCrowd’s platform. While more then 1000 have filled a survey at least once, only seventy eight of them who consumed Mannitol more than 6 months, are included in the results:
To date, 56 % report of improvement in their Parkinson’s grade and symptoms despite the disease progressive nature. 7% reported no change in their situation and 37% showed deterioration in their status. i.e 63% of the patients reported either an improvement or no change after 6-15 months with Mannitol, which is an encouraging finding based on the continued progressive deterioration of PD.
90% regained sense of smell;
86% improved their facial expression
81% improved their gait
80% had less hallucinations.
78% showed improvement in Scale of Energy and Vitality
77% showed improvement in their muscle cramps
For further details, on this and other indications, join our crowd-based surveys at: clinicrowd.info
A few important notes:
CliniCrowd does not provide any medical advice.
This is not a clinical trial, this is based on reports made by patients who chose to report back on the status of their disease while taking Mannitol in addition to the regular drugs prescribed by their Medical Doctors.
CliniCrowd does not sell Mannitol and is not affiliated with any Mannitol manufacturer.
The results are strictly based on patients who decided to take Mannitol and report back to the community.
The reports are based on surveys similar to questionnaires which are frequently used in clinical trials.