Morphine with gabapentin

[Shiannerenee]

Hi has anyone any advice concerning the use of oramorph with gabapentin?

[Bananas5]

Have you been prescribed both together?

Morphine slows down your GI tract. This may allow your body to absorb more gabapentin.

What might happen:

The amount of gabapentin in your blood may increase and cause more side effects than expected.

[mum-norton in reply to Bananas5]

dont take it, gabapentin is a nightmare,

[mikewitney]

Yea it's fine gabapentine is background protection and oramorph will act quick on flare ups. I've been on oramorph for 3 years now and mixed it with pregabalin and gabapentine

[hypercat54]

My sister is on both and has never reported any problems. x

[happytulip]

Both can cause drowsiness and mild drop in blood pressure but as long as you take it sensibly and increase any doses slowly then you should be fine.

I was on oramorph and gabapentin for a year, then switched to oramorph and pregabalin which was more effective.

I haven't had any problems with either. Its important to live a life without pain as pain reduces mobility and that has far more risk factors.

[Delzek]

Hi I am currently on Oramorph and Zomorph, I stopped taking Gabbapentin so they put me on Pregabalin which I have also stopped taking , I did have a genuine reason for stopping even though both helped me immensely I ended up sort of sleepwalking through the day and nights a week would go by and I thought it was only a day! Even though I dislike pain I would rather endure some pain than be like a zombie! My Dr agreed that if it was affecting me the way it was I could come off slowly as I was on very high amounts of Gabbapentin . I have said in previous posts that medication works in different ways with different people,so what works for you may not work for me and vice versa!

[Jay67]

I have been taking oramorph and gabapentin for a long time now. These drugs make you sleepy and forgetful. Also I have had problems with short term memory. Since visiting the pain speacialist I’m on dulexetine and pregaba. You have to realise these drugs mess up your system long term. I have to take these drugs to ease the pain after microduseceomy op. I still get pain on buttocks and calf. Recent mri showed nothing abnormal. I hope you get well or at the very least train yourself to manage the pain. It never goes away. Then again everyone responds differently to pain. I’m hopeless!!!

[Bubbles84]

I am on both. One question through is it liquid morphine or pill form? I have had know problems

[Cloud9-71]

Start low and slow with gabapentin.. it takes a while to kick in too.. are you taking much oramorph? would you be better with a slow release morphine twice a day instead. It gives you more continous pain relief even at night andyou can keep the oramorph for emergencies.

Good luck

[Fatabelly]

In my experience (6+yrs) I’ve never had any problems taking Gabapentin & Oramorph. They’re different types of drug so it’s absolutely safe.

[wheezybronch]

I was on 40 mg slow release morphine ( Zormorph ) with Sevredol 10 mg (instant morphine) for break through pain, I normally took 20 mg as 10 mg did nothing, I had 400 mg Gabapentin three times a day, this went on for ten years with pain seemingly taking over my life. I decided to go "cold turkey" with the morphine and stopped taking it, at the same time I raised Gabapentin to 600 mg three times a day. I have extensive osteoarthritis, Bronchiectasis, Tracheobronchomalacia, OSA, and have been diagnosed with Fibromyalgia. These drugs on their own or in tandem don't help me very much, I am thinking of stopping the Gabapentin. I really want to try Ketamine but have had no luck so far with anyone willing to prescribe it as it is addictive !!! Like morphine, Gabapentin, codeine isn't ?? I am afraid I have been negative and I don't think that you should be put off trying the combination, I know people who say it helps a lot, good luck to you.

[Bramble71]

I take Gabapentin and Zomorph pills and then use Oramorph for breakthrough pain. The side effects, along with the pain, have changed my life. I can no longer work, for example. I have cognitive issues (couldn't even do my own job after 3 years in it), couldn't form patterns or methods, I have memory problems, I'm sleepy all the time, I can sleep about 18 hours a day quite easily, can't concentrate. I hate the side effects but i hate the pain more so i keep taking them. Ugh.

Everyone reacts differently, though, as you can see in the responses, and it's a matter of finding the right dose for you to achieve the outcome you want.