Hi my most recent (3rd line) chemo has not been effective and latest ct scan shows enlarged lymph nodes in chest and abdomen, also CA125 has risen to over 700 (when last tested 3 weeks ago). I have been having quite a bit of abdominal discomfort, also lower back pain, have any of you ladies experienced similar symptoms? Going to see oncologist in 2 weeks, when we will discuss treatment options, but he said he would arrange for me to have an MRI scan also bone scan. Does this disease follow any kind of pattern? I would like to know what to expect!