Cinvanti (aprepitant) for nausea? Side effects?

[Sashay2020]

Hello my teal sisters. Has anyone had Cinvanti (aprepitant) for nausea? During frontline chemo ondansetron was included in my prechemo IV. Very effective and minimal side effects. I didn’t know my new oncologist changed to Cinvanti (aprepitant). The morning after chemo, I awoke around 3:00 am with an excruciating headache that lasted hours. I finally knocked it back with prescription pain meds and held it at bay until this evening. I emailed my oncologist to let him know. Has anyone had this medication? Any headaches? I have since read online that headaches are a common side effect. Wondering how many days before they stop. Thanks and best wishes from Louisiana to all.

Sashay

[Morini]

Hi, I had Aprepitant, Ondansetron, Dexamethasone and Metoclopramide for anti sickness. It was very effective, I experienced no nausea at all, but I had fatigue, visual disturbance and bouts of diarrhoea or constipation but nothing like the headache that you describe. I am thinking of you and hoping that you are feeling better soon. xx

[Sashay2020 in reply to Morini]

Thanks for responding, Morini. Glad the meds worked well for you. I have not had nausea, but I will ask my oncologist to remove Aprepitant and go back to Ondansetron. I’m hoping the headaches will stop tomorrow when most of the drug will be out of my system. I have Ondansetron pills which oncologist prescribed if I need them. Take care of yourself,

Sashay

[delia2]

Hi. I had it in my premeds last time I had chemo. I didn’t get headaches though. I honk I had odensatron with it but maybe not. If that’s causing the problem they can probably change it. Xx

[Sashay2020 in reply to delia2]

Thanks, Delia. I’m sure he will switch me back to Ondansetron for my next chemo. I did have trouble with tachycardia. I have had bouts of rapid heartbeats since my teens. Oncologist is ordering a baseline heart ultrasound for me. Sounds like a good idea. Take care,

Sashay

[Summergold2]

Hi Sashay I had everything!!!Dexamethasone, Kytril, and Cinvanti, Pepcid, and Benadryl for the reaction I had to Doxil. Cant comment on any headaches but nausea, constipation and really bad cold night sweats! Hope you can get that all worked out. Take care I am sure they can come up with something in their bag of tricks!Debbie

[Sashay2020 in reply to Summergold2]

So you had the night sweats, too. Did they diminish over time? I hope so!Sashay

[Summergold2]

they lasted for about 3 to 4 days and then much better that was right after chemo!

[Sashay2020 in reply to Summergold2]

That’s good to hear. Thanks so much for this info. 🙂

[Laz66]

Hi there, I had this on my last cycle as my usual ( akinseo) was out of stock! It didn’t give me a headache. I am usually off the planet after chemo anyway but no headaches. X

[Sashay2020]

Thanks. My headaches are beginning to fade.