Prolia Side Effects: Has anyone who is... - Osteoporosis Support

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Prolia Side Effects

great_clothes profile image
13 Replies

Has anyone who is on Prolia injections become more tired?

If yes, what have you done about it?

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great_clothes
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13 Replies
Grandk23sc profile image
Grandk23sc

I haven't noticed fatigue and after my 9th dose even the joint pain has diminished. The jury will be out until I see the next bone scan!

Makeshift profile image
Makeshift

I was on it for Five years without being tired because of it. I have now been off for 1 1/2 years

in reply toMakeshift

How did you get off Prolia? Did you have to transition?

Makeshift profile image
Makeshift in reply to

Correction; I have been off Prolia for 2 1/2 years not 1 1/2 years as I stated. They used Reclast infusion for two years to transition ; I had zero side effects with it. They first tried to just take me off Prolia for a 1 year drug Holliday; with no transition! I had to speak up for myself and show my concerns and inform them to read about it. I thank this site information and the members.

in reply toMakeshift

Thanks. I have been on 3 years and have dental problems. I want to get off at some point but doc says my scans show positive response. A dilemma.

StuyTown profile image
StuyTown in reply to

Can you tell me what kind of dental problems you are having?

Finnegan777 profile image
Finnegan777

yes, I feel fatigue all the time, sometimes my legs feel very rubbery, just do not feel well. I am thinking it’s from the Prolia. . I have been on it for a year and a half now they tell me I have a lung infection that showed up on an x-ray, which infection can be a side effect. Yikes, last dexa scan showed no improvement from the Prolia, so doctor said we won’t do any more bone scans??? I have a very bad case of osteoporosis, so I am between a rock and a hard place. I am trying to get an appointment with an endocrinologist. it is very distressing this, OP.

MayGodBlessYou profile image
MayGodBlessYou in reply toFinnegan777

may i ask what you had the x-ray for?

MayGodBlessYou profile image
MayGodBlessYou in reply toFinnegan777

will they give you treatment / antibiotic / test for the lung infection? my Mum's been on prolia several years, has lung infection, though not coughing or anything, only a couple of coughs in the past year, would'nt've known she even had it except for a scan.

Mum a few years ago had some cellulitis in her hand. i attribute it to the drug. not sure about the lung infection.

also has fatigue, i think due to the drug, although she is elderly. i observed fatigue for like 3 months out of the 6 month dose, then improving.

great_clothes profile image
great_clothes

Thank you for the suggestions

Deb967 profile image
Deb967

I had only 1 Prolia and I am exausted all the time. I had many side effects from Prolia but I never thought this tiredness is from it too. Guess another side effect to add to my list.

Songbird6 profile image
Songbird6

I have had one injection so far, in May, and since then I have had incredible tiredness since. I have been trying to have a sleep during the day, especially if I want to socialise or even watch some TV in the evening. I took early retirement in February, just as well because I don't think I would be able to cope with work and general home life, the way I feel. Definitely didn't feel this tired before Prolia or when I was on Evenity/Romosozumab. I can't say I like napping during the day, even to read sends me to sleep!! 😏

MayGodBlessYou profile image
MayGodBlessYou

i am pretty sure my Mum has exhaustion from the drug. she is elderly too but i can tell it is additional tiredness over the years. among other things. it's possible i notice the tiredness relent a little in the last couple of months of a 6-monthly dose. it's heartbreaking for me.

for the first 4 years it wasn't much of an issue.

health care providers say nothing about it, because they don't know, and because they're not told by the manufacturer marketing

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